(Q36123295)

12 August 2017

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title

Predicting inhibitory drug-drug interactions and evaluating drug interaction reports using inhibition constants (English)

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12 August 2017

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Kenneth A Bachmann

1

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12 August 2017

Jeffrey D Lewis

series ordinal

2

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12 August 2017

language of work or name

English

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publication date

10 May 2005

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Annals of Pharmacotherapy

12 August 2017

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12 August 2017

39

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12 August 2017

6

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12 August 2017

1064-1072

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The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective

12 August 2017

1 reference

The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective.

21 January 2018

1 reference

Qualitative and quantitative assessment of drug-drug interaction potential in man, based on Ki, IC50 and inhibitor concentration.

21 January 2018

1 reference

Quantitative prediction of in vivo drug-drug interactions from in vitro data based on physiological pharmacokinetics: use of maximum unbound concentration of inhibitor at the inlet to the liver

21 January 2018

1 reference

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

21 January 2018

1 reference

Screening of drug candidates for their drug--drug interaction potential

21 January 2018

1 reference

Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors

21 January 2018

1 reference

Predicting drug clearance from recombinantly expressed CYPs: intersystem extrapolation factors

21 January 2018

1 reference

Implications of the allosteric kinetics of cytochrome P450s

21 January 2018

1 reference

In vitro and pharmacophore insights into CYP3A enzymes

21 January 2018

1 reference

Atypical Enzyme Kinetics: Their Effect on In Vitro-In Vivo Pharmacokinetic Predictions and Drug Interactions

21 January 2018

1 reference

The human CYP3A subfamily: practical considerations

21 January 2018

1 reference

Drug Metabolism and Drug Interactions: Application and Clinical Value of In Vitro Models

21 January 2018

1 reference

The complexities of hepatic drug transport: current knowledge and emerging concepts.

21 January 2018

1 reference

Transporter-Enzyme Interactions: Implications for Predicting Drug-Drug Interactions from In Vitro Data

21 January 2018

1 reference

Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

21 January 2018

1 reference

An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1345/APH.1E508

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release_qq565kel3baabafenujmprjby4

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qq565kel3baabafenujmprjby4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference