(Q40343599)

English

Evaluation of human liver slices and reporter gene assays as systems for predicting the cytochrome p450 induction potential of drugs in vivo in humans

scientific article published on January 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Evaluation of human liver slices and reporter gene assays as systems for predicting the cytochrome p450 induction potential of drugs in vivo in humans (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

Kajsa P Persson

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Susanne Ekehed

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Charlotta Otter

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

E S Mareike Lutz

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Jane McPheat

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Collen M Masimirembwa

6

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Tommy B Andersson

7

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2006

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

56-69

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism

1 reference

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Plasma concentrations of betamethasone after topical application of betamethasone 17-valerate: comparison with oral administration

1 reference

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21 January 2018

Pharmacokinetics of indomethacin

1 reference

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21 January 2018

Single- and multiple-dose pharmacokinetic comparison of a sustained-release tablet and conventional tablets of naproxen in healthy volunteers.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-005-8812-5

21 January 2018

Faster clearance of sustained release verapamil in men versus women: continuing observations on sex-specific differences after oral administration of verapamil

1 reference

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12 December 2020

based on heuristic

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The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of pravastatin: mechanisms of pharmacokinetic events

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

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Concomitant use of mirtazapine and phenytoin: a drug-drug interaction study in healthy male subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

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Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of troglitazone, a PPAR-gamma agonist, in patients with hepatic insufficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of antipyrine and rifampin on the metabolism of diazepam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cytochrome P450 2B6 and 3A4 expression by phenobarbital and cyclophosphamide in cultured human liver slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single- and multiple-dose pharmacokinetics of bosentan and its interaction with ketoconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of the warfarin-rifampin drug interaction in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flumazenil reduces midazolam-induced cognitive impairment without altering pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and effect on caffeine metabolism of the proton pump inhibitors, omeprazole, lansoprazole, and pantoprazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy males

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of modafinil at steady state on the single-dose pharmacokinetic profile of warfarin in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of chlorpromazine and key metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome 1A1 induction by primaquine in human hepatocytes and HepG2 cells: absence of binding to the aryl hydrocarbon receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chronic phenobarbital on verapamil disposition in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of drug interaction between omeprazole, lansoprazole, pantoprazole and theophylline

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cytochrome P4501A1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective liver enzyme induction by carbamazepine and phenytoin in Chinese epileptics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability of carbamazepine from four different products and the occurrence of side effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nifedipine-rifampin interaction. Evidence for induction of gut wall metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of in vivo/in vitro correlations for 50 mg and 250 mg primidone tablets

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the kinetic disposition and metabolism of E3810, a new proton pump inhibitor, and omeprazole in relation to S-mephenytoin 4'-hydroxylation status

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

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Molecular cloning of the guinea pig CYP1A2 gene 5'-flanking region: identification of functional aromatic hydrocarbon response element and characterization of CYP1A2 expression in GPC16 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics of lovastatin extended-release tablets and lovastatin immediate-release tablets in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different structural requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-affinity ligand binding and receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of significant pharmacokinetic and pharmacodynamic interactions between artemether and quinoline antimalarials

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between simvastatin and troglitazone or pioglitazone in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of felbamate on the pharmacokinetics of phenobarbital

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between phenobarbital and diphenylhydantoin in animals and in epileptic patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Artemisinin pharmacokinetics in healthy adults after 250, 500 and 1000 mg single oral doses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concurrent administration of donepezil HCl and cimetidine: assessment of pharmacokinetic changes following single and multiple doses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-dose kinetics of primidone in acute viral hepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rifampin drastically reduces plasma concentrations and effects of oral midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of dexamethasone and its relationship to dexamethasone suppression test outcome in depressed patients and healthy control subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinidine single dose pharmacokinetics and pharmacodynamics are unaltered by omeprazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/16328606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-005-8812-5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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