(Q34283856)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

review article

1 reference

title

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

LeCluyse EL

series ordinal

1

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 July 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Pharmaceutical Sciences

8 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

343-368

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

Delayed assembly of desmosomes in keratinocytes with disrupted classic-cadherin-mediated cell adhesion by a dominant negative mutant

8 November 2019

cites work

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7 January 2021

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

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7 January 2021

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

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7 January 2021

Connexin family of gap junction proteins

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7 January 2021

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

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7 January 2021

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

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7 January 2021

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

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7 January 2021

Modeling of pharmacokinetic/pharmacodynamic (PK/PD) relationships: concepts and perspectives

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7 January 2021

Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450.

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7 January 2021

The use of liver spheroids as an in vitro model for studying induction of the stress response as a marker of chemical toxicity

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7 January 2021

Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

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7 January 2021

Phalloidin-induced cholestasis: a microfilament-mediated change in junctional complex permeability

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7 January 2021

Long-term primary cultures of adult human hepatocytes

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7 January 2021

Strategies for transcriptional activation by steroid/nuclear receptors

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7 January 2021

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

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7 January 2021

The cytoplasmic domain of adherens-type junctions

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7 January 2021

The relationship between intermediate filaments and microfilaments before and during the formation of desmosomes and adherens-type junctions in mouse epidermal keratinocytes

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7 January 2021

Effect of cell density and epidermal growth factor on the inducible expression of CYP3A and CYP1A genes in human hepatocytes in primary culture

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7 January 2021

Liver cell models in in vitro toxicology

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7 January 2021

Use of human hepatocyte cultures for drug metabolism studies

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7 January 2021

Use of hepatocyte cultures for the study of hepatotoxic compounds

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7 January 2021

Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation

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7 January 2021

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

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https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors

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7 January 2021

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

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7 January 2021

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

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7 January 2021

Regulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherin

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7 January 2021

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

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7 January 2021

Drug metabolism in hepatocyte sandwich cultures of rats and humans

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7 January 2021

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

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7 January 2021

Changes in cellular distribution of connexins 32 and 26 during formation of gap junctions in primary cultures of rat hepatocytes

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7 January 2021

Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration

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7 January 2021

Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes

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7 January 2021

Regeneration and maintenance of bile canalicular networks in collagen-sandwiched hepatocytes.

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7 January 2021

Intercellular communication in primary cultures of putative preneoplastic and 'normal' hepatocytes.

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7 January 2021

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

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7 January 2021

Cadherin function is required for human keratinocytes to assemble desmosomes and stratify in response to calcium

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7 January 2021

Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin.

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7 January 2021

Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction.

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7 January 2021

Primary human hepatocytes as a tool for the evaluation of structure-activity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin

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7 January 2021

Separate and interactive regulation of cytochrome P450 3A4 by triiodothyronine, dexamethasone, and growth hormone in cultured hepatocytes.

1 reference

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7 January 2021

Calcium-induced changes in cytoskeleton and motility of cultured human keratinocytes

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7 January 2021

In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone

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7 January 2021

Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity

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7 January 2021

Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules

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7 January 2021

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

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7 January 2021

Expression of cytochrome P-450 enzymes in cultured human hepatocytes

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7 January 2021

Transmembrane control of cadherin-mediated cell-cell adhesion

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7 January 2021

Communication via gap junctions modulates bile secretion in the isolated perfused rat liver

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7 January 2021

Altered Hepatic Blood Flow and Drug Disposition1

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7 January 2021

The alcohol-inducible form of cytochrome P450 (CYP 2E1): role in toxicology and regulation of expression

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Quantitative RT-PCR Measurement of Human Cytochrome P-450s: Application to Drug Induction Studies

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https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Morphogenesis of the polarized epithelial cell phenotype

1 reference

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7 January 2021

Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios: coincidence with plasma clearance and breath test

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7 January 2021

Serum-free, long-term cultures of human hepatocytes: maintenance of cell morphology, transcription factors, and liver-specific functions

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix

1 reference

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7 January 2021

Gap junctional communication and regulation of the glycogenic response to insulin by cell density and glucocorticoids in cultured fetal rat hepatocytes

1 reference

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7 January 2021

Influence of extracellular matrix overlay on phenobarbital-mediated induction of CYP2B1, 2B2, and 3A1 genes in primary adult rat hepatocyte culture

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https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

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https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Cadherin cell adhesion receptors as a morphogenetic regulator

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7 January 2021

Cadherins in cancer: implications for invasion and metastasis

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https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Motility of bile canaliculi in the living animal: implications for bile flow

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https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Phenobarbital induction of cytochromes P-450. High-level long-term responsiveness of primary rat hepatocyte cultures to drug induction, and glucocorticoid dependence of the phenobarbital response

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E-cadherin

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Coactivator and corepressor complexes in nuclear receptor function

1 reference

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7 January 2021

An immunofluorescence study of the calcium-induced coordinated reorganization of microfilaments, keratin intermediate filaments, and microtubules in cultured human epidermal keratinocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2801%2900135-X

7 January 2021

10.1016/S0928-0987(01)00135-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408150%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference