(Q35185727)

7 August 2017

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title

Pharmacokinetic interactions with rifampicin : clinical relevance (English)

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7 August 2017

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Mikko Niemi

1

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author name string

Janne T Backman

2

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7 August 2017

Martin F Fromm

3

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7 August 2017

Pertti J Neuvonen

4

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7 August 2017

Kari T Kivistö

5

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7 August 2017

language of work or name

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1 January 2003

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Clinical Pharmacokinetics

7 August 2017

published in

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7 August 2017

volume

42

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7 August 2017

issue

9

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7 August 2017

page(s)

819-850

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Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine

7 August 2017

cites work

1 reference

12 December 2020

Effect of diphenylhydantoin on cortisol kinetics in humans

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12 December 2020

Comparative effects of rifampin and/or probenecid on the pharmacokinetics of temazepam and nitrazepam

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12 December 2020

Concentrations and effects of zopiclone are greatly reduced by rifampicin

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12 December 2020

A study of interaction of a low-dose combination oral contraceptive with anti-tubercular drugs

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12 December 2020

Drug interactions in use of dapsone for Pneumocystis carinii prophylaxis

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12 December 2020

Triazolam is ineffective in patients taking rifampin

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12 December 2020

Interactions between FK506 and rifampicin or erythromycin in pediatric liver recipients

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12 December 2020

Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation

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12 December 2020

Effect of phenytoin on meperidine clearance and normeperidine formation

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12 December 2020

Clinical pharmacokinetic considerations in the treatment of patients with leprosy

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12 December 2020

Effect of diphenylhydantoin on the metabolism of dicoumarol in man.

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12 December 2020

Effect of rifampin on chloramphenicol levels

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12 December 2020

Altered prednisolone pharmacokinetics in patients treated with rifampicin

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12 December 2020

Treatment of HIV-related tuberculosis in the era of effective antiretroviral therapy

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12 December 2020

Therapeutic implications of drug interactions in the treatment of human immunodeficiency virus-related tuberculosis

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12 December 2020

A link between liver microsomal enzyme activity and thyroid hormone metabolism in man

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12 December 2020

Reduced serum levels of clarithromycin in patients treated with multidrug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection

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12 December 2020

Effects of Diphenylhydantoin, Phenobarbital, and Diazepam on the Metabolism of Methylprednisolone and Its Sodium Succinate

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12 December 2020

Effects of erythromycin or rifampin on losartan pharmacokinetics in healthy volunteers

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12 December 2020

Pharmacokinetic interaction of clozapine and rifampicin in a forensic patient with an atypical mycobacterial infection

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12 December 2020

Rifampin-induced release of hydrazine from isoniazid. A possible cause of hepatitis during treatment of tuberculosis with regimens containing isoniazid and rifampin

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12 December 2020

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

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12 December 2020

The effects of inducing agents on cytochrome P450 and UDP-glucuronyltransferase activities in human HEPG2 hepatoma cells

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12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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12 December 2020

Effect of rifampin on plasma concentrations of mefloquine in healthy volunteers.

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12 December 2020

Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR.

1 reference

12 December 2020

The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin

1 reference

12 December 2020

Morning spot and 24-hour urinary 6 beta-hydroxycortisol to cortisol ratios: intraindividual variability and correlation under basal conditions and conditions of CYP 3A4 induction

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12 December 2020

Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters

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12 December 2020

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

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12 December 2020

Effects of cytochrome P450 inducers on 17alpha-ethinyloestradiol (EE2) conjugation by primary human hepatocytes

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12 December 2020

The effect of rifampin administration on the disposition of fexofenadine

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12 December 2020

Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily

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12 December 2020

Loss of analgesic effect of morphine due to coadministration of rifampin

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12 December 2020

Effect of rifampicin on the pharmacokinetics and pharmacodynamics of glimepiride

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12 December 2020

Letter: Rifampicin and cortisone replacement therapy

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12 December 2020

Rifampin-induced deterioration in steroid-dependent asthma

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12 December 2020

The effect of antipyrine and rifampin on the metabolism of diazepam.

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12 December 2020

Influence of debrisoquin phenotype on the inducibility of propranolol metabolism

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12 December 2020

Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

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12 December 2020

Acute cardiac failure during treatment with digitoxin--an interaction with rifampicin

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12 December 2020

Clinical pharmacokinetics of morphine

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12 December 2020

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12 December 2020

Studies on dexamethasone metabolism in man: effect of diphenylhydantoin

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12 December 2020

Influence of rifampicin and isoniazid on the kinetics of phenytoin

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12 December 2020

Case report: nifedipine-rifampicin interaction attenuates the effect on blood pressure in a patient with essential hypertension

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12 December 2020

Increased nonrenal clearance of cimetidine during antituberculous therapy

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12 December 2020

The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions

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12 December 2020

A possible drug interaction between rifampicin and enalapril

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12 December 2020

Biochemistry and molecular biology of the human CYP2C subfamily

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12 December 2020

The induction effect of rifampicin on activity of mephenytoin 4'-hydroxylase related to M1 mutation of CYP2C19 and gene dose

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12 December 2020

Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele

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12 December 2020

Pharmacokinetic study of the interaction between rifampicin and ketoconazole

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12 December 2020

Clinical pharmacokinetics of lorazepam. I. Absorption and disposition of oral 14C-lorazepam

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12 December 2020

Effect of rifampicin on metoprolol and antipyrine kinetics

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12 December 2020

The lignocaine metabolite (MEGX) liver function test and P-450 induction in humans

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12 December 2020

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12 December 2020

Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin

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12 December 2020

Effect of prednisolone and rifampin on isoniazid metabolism in slow and rapid inactivators of isoniazid

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12 December 2020

Oxazepam pharmacokinetics in patients with epilepsy treated long-term with phenytoin alone or in combination with phenobarbitone

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12 December 2020

Effect of rifampin on the plasma concentration and the clinical effect of haloperidol concomitantly administered to schizophrenic patients

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12 December 2020

Interaction of bisoprolol with cimetidine and rifampicin

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12 December 2020

Pharmacokinetic profile of nicorandil in humans: an overview

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12 December 2020

Characterization of human small intestinal cytochromes P-450.

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12 December 2020

Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine.

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12 December 2020

Near-total reduction in verapamil bioavailability by rifampin. Electrocardiographic correlates

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12 December 2020

Pharmacokinetics and metabolism of nateglinide in humans.

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12 December 2020

Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin

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12 December 2020

Effects of microsomal enzyme induction on paracetamol metabolism in man

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12 December 2020

Pharmacokinetics and pharmacodynamics of alprazolam after oral and IV administration

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12 December 2020

Simultaneous assessment of CYP3A4 and CYP1A2 activity in vivo with alprazolam and caffeine.

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12 December 2020

Rifampin-induced nonresponsiveness of giant cell arteritis to prednisone treatment

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12 December 2020

Clinical Pharmacokinetics of Oxazepam and Lorazepam

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12 December 2020

[Study of the influence of rifampin on the anticoagulant effect of acenocoumarol]

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12 December 2020

Rifampin decreases the plasma concentrations and effects of repaglinide

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12 December 2020

The pharmacokinetics of midazolam in man.

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12 December 2020

Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva.

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12 December 2020

Induction of propranolol metabolism by rifampicin

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12 December 2020

Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays

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12 December 2020

Interaction of gliclazide and rifampicin

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12 December 2020

The influence of enzyme induction on polymorphic sparteine oxidation

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12 December 2020

Interaction of sodium warfarin and rifampin. Studies in man.

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12 December 2020

Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes

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12 December 2020

Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by isoniazid in humans

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12 December 2020

Antituberculosis agents and carbamazepine

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12 December 2020

Human P-glycoprotein transports cyclosporin A and FK506.

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12 December 2020

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12 December 2020

Anticonvulsant therapy increases fentanyl requirements during anaesthesia for craniotomy

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12 December 2020

Updated clinical safety experience with fluvastatin

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12 December 2020

Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy

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12 December 2020

Oxidative metabolism of zolpidem by human liver cytochrome P450S

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12 December 2020

Interaction of chronic daily warfarin therapy and rifampin

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12 December 2020

Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole

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12 December 2020

Effect of rifampicin treatment on the kinetics of mexiletine

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12 December 2020

Interaction between carbamazepine and antituberculosis agents.

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12 December 2020

The mechanism of the warfarin-rifampin drug interaction in humans

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12 December 2020

P-glycoprotein-mediated transcellular transport of MDR-reversing agents

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12 December 2020

Interaction of tertatolol with rifampicin and ranitidine pharmacokinetics and antihypertensive activity

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12 December 2020

Human MDR1 and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene

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12 December 2020

In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s

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12 December 2020

Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers

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12 December 2020

Drug interaction: rifampicin and glibenclamide.

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12 December 2020

The effects of rifampin and rifabutin on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive

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12 December 2020

Mealtime glucose regulation with nateglinide in healthy volunteers: comparison with repaglinide and placebo

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12 December 2020

Enzyme induction in the elderly: Effect of rifampin on the pharmacokinetics and pharmacodynamics of propafenone

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12 December 2020

Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype

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12 December 2020

Cytochrome P-450 3A4 and 2C8 are involved in zopiclone metabolism.

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12 December 2020

Interaction of Ketoconazole with Rifampin and Isoniazid

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12 December 2020

Effectiveness of prednisolone during phenytoin therapy

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12 December 2020

Interaction of rifampin and digitoxin

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12 December 2020

New oral therapies for type 2 diabetes mellitus: The glitazones or insulin sensitizers

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12 December 2020

Reduced plasma nisoldipine concentrations in phenytoin-treated patients with epilepsy

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12 December 2020

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

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12 December 2020

Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin.

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12 December 2020

Multiple-dose pharmacokinetics of concurrent oral ciprofloxacin and rifampin therapy in elderly patients

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12 December 2020

Oxidative versus conjugative biotransformation of temazepam

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12 December 2020

Pharmacokinetic study of the interaction between rifampin and delavirdine mesylate

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12 December 2020

Gut wall metabolism of verapamil in older people: effects of rifampicin-mediated enzyme induction

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12 December 2020

A hepatic graft tuberculosis transmitted from a living-related donor

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12 December 2020

Pharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy males

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12 December 2020

Does rifampicin increase serum levels of testosterone and oestradiol by inducing sex hormone binding globulin capacity?

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12 December 2020

Expression of cytochrome P-450 enzymes in cultured human hepatocytes

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12 December 2020

Purification of two cytochrome P450 isozymes related to CYP2A and CYP3A gene families from monkey (baboon, Papio papio) liver microsomes. Cross reactivity with human forms

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12 December 2020

[The effects of antituberculosis drugs on the pharmacokinetics of digitoxin (author's transl)]

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12 December 2020

Rifampicin reduces effectiveness and bioavailability of prednisolone.

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12 December 2020

Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans

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12 December 2020

Quinidine-Rifampin Interaction

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12 December 2020

Influence of rifampin on fleroxacin pharmacokinetics

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12 December 2020

Rifampin reduces plasma concentrations and effects of zolpidem.

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12 December 2020

In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors

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12 December 2020

Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin

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12 December 2020

The effect of rifampin on the pharmacokinetics of oral and intravenous ondansetron

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12 December 2020

Effects of rifampicin and cimetidine on pharmacokinetics and pharmacodynamics of lamotrigine in healthy subjects

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12 December 2020

Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor

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12 December 2020

Rifampin-induced selective serotonin reuptake inhibitor withdrawal syndrome in a patient treated with sertraline

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12 December 2020

Rifampicin and methadone withdrawal

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12 December 2020

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

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12 December 2020

Tamoxifen and toremifene concentrations in plasma are greatly decreased by rifampin

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12 December 2020

Drug interactions with fluconazole

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12 December 2020

Induction of zidovudine glucuronidation and amination pathways by rifampicin in HIV-infected patients

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12 December 2020

Effect of tuberculostatic agents on the response of serum growth hormone and immunoreactive insulin to intravenous tolbutamide, and on the half-life of tolbutamide

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12 December 2020

The pharmacokinetics in man of a combination of rifampicin and trimethoprim

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12 December 2020

Consequences of rifampicin treatment on propafenone disposition in extensive and poor metabolizers of CYP2D6

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12 December 2020

Concentrations and effects of buspirone are considerably reduced by rifampicin

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12 December 2020

CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide

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12 December 2020

The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients

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12 December 2020

Rifampin-Induced Methadone Withdrawal

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12 December 2020

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

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12 December 2020

Theophylline metabolism in human liver microsomes: inhibition studies.

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12 December 2020

Methadone maintenance and tuberculosis treatment.

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12 December 2020

Effect of rifampin on theophylline disposition

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12 December 2020

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

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12 December 2020

Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells

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12 December 2020

Glimepiride. A review of its use in the management of type 2 diabetes mellitus

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12 December 2020

Pharmacokinetics of aldosterone in patients with Addison's disease: effect of rifampicin treatment on glucocorticoid and mineralocorticoid metabolism

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12 December 2020

Induction of CYP2C genes in human hepatocytes in primary culture

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12 December 2020

Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: relationship to the presence of immunoidentified cytochrome P-450IID1.

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12 December 2020

Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers

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12 December 2020

Significant reduction of sertraline plasma levels by carbamazepine and phenytoin

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12 December 2020

Impact of environmental and genetic factors on codeine analgesia

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12 December 2020

Interaction of rifampin and glucocorticoids. Adverse effect on renal allograft function

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12 December 2020

The effect of rifampicin on sulphapyridine plasma concentrations following sulphasalazine administration

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12 December 2020

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

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12 December 2020

Interaction of chloramphenicol and rifampin

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12 December 2020

Acute rejection and massive cyclosporine requirements in heart transplant recipients treated with rifampin

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12 December 2020

The nifedipine-rifampin interaction. Evidence for induction of gut wall metabolism

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12 December 2020

Rifampin-induced methadone withdrawal in AIDS

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12 December 2020

Structural mechanism for rifampicin inhibition of bacterial rna polymerase

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12 December 2020

The effect of rifampicin on the pharmacokinetics of doxycycline

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12 December 2020

Failure of Rifampin to Induce the Metabolism of Clonidine in Normal Volunteers

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12 December 2020

Influence of rifampin on tocainide pharmacokinetics in humans.

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12 December 2020

Drug metabolism in hepatocyte sandwich cultures of rats and humans

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12 December 2020

Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction

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12 December 2020

Identification of P450 enzymes involved in metabolism of verapamil in humans

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12 December 2020

Influence of rifampicin on drug metabolism: differences between hexobarbital and antipyrine

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12 December 2020

Reduced felodipine bioavailability in patients taking anticonvulsants

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12 December 2020

Effect of rifampicin on the pharmacokinetics of itraconazole in normal volunteers and AIDS patients

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12 December 2020

In vivo modulation of CYP enzymes by quinidine and rifampin

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12 December 2020

Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines

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12 December 2020

Steady-state serum pharmacokinetics of novobiocin and rifampin alone and in combination

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12 December 2020

The effect of rifampin treatment on intestinal expression of human MRP transporters

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12 December 2020

Effect of rifampicin administration on theophylline pharmacokinetics in humans

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12 December 2020

Drug interaction between rifampin and nortriptyline: a case report

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12 December 2020

Differential effects of valproic acid and enzyme-inducing anticonvulsants on nimodipine pharmacokinetics in epileptic patients

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12 December 2020

Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

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12 December 2020

Marked enhancement by rifampicin and lack of effect of isoniazid on the elimination of quinine in man.

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12 December 2020

Induction of theophylline clearance by rifampin and rifabutin in healthy male volunteers.

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12 December 2020

Renal allograft dysfunction associated with rifampin-tacrolimus interaction

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12 December 2020

Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily.

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12 December 2020

Theophylline-rifampicin interaction: non-selective induction of theophylline metabolic pathways

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12 December 2020

Comparative pharmacokinetics and pharmacodynamics of the rifamycin antibacterials

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12 December 2020

Pharmacokinetic factors in the modern drug treatment of tuberculosis.

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12 December 2020

Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4

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12 December 2020

Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide

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12 December 2020

Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers

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12 December 2020

Human liver microsomal N-hydroxylation of dapsone by cytochrome P-4503A4

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12 December 2020

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

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12 December 2020

Divergent effects of different enzyme-inducing agents on endogenous and exogenous testosterone

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12 December 2020

Influence of rifampin on the pharmacokinetics of pefloxacin

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12 December 2020

Rifampicin treatment greatly increases the apparent oral clearance of quinidine

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12 December 2020

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

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12 December 2020

OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

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12 December 2020

Inhibition by Rifampin of the Anticoagulant Effect of Phenprocoumon

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12 December 2020

Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells.

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12 December 2020

Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

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12 December 2020

Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation

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12 December 2020

P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs

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12 December 2020

Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver

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12 December 2020

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

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12 December 2020

Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue

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12 December 2020

Regulation of cyp3a gene transcription by the pregnane x receptor

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12 December 2020

Adverse effect of rifampicin administration on steroid-dependent asthma

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12 December 2020

The effect of single dose of rifampicin on the pharmacokinetics of oral nifedipine

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12 December 2020

The effects of rifampicin on the pharmacokinetics and pharmacodynamics of orally administered nilvadipine to healthy subjects

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12 December 2020

Optimum Treatment of Staphylococcal Infections

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12 December 2020

Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects

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12 December 2020

Rapid metabolism of cyclosporin and prednisone in kidney transplant patients on tuberculostatic treatment

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12 December 2020

Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations

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12 December 2020

Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.

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12 December 2020

Effect of rifampin and tobacco smoking on the pharmacokinetics of ropivacaine

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12 December 2020

Toxic hepatitis with isoniazid and rifampin. A meta-analysis

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12 December 2020

Diazepam interaction with antituberculosis drugs.

1 reference

12 December 2020

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone

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12 December 2020

Rifampin drastically reduces plasma concentrations and effects of oral midazolam.

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12 December 2020

The role of cytochrome P450 3A4 in alfentanil clearance. Implications for interindividual variability in disposition and perioperative drug interactions.

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12 December 2020

In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (±)-fluvastatin*

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12 December 2020

The effect of enzyme induction on the metabolism of disopyramide in man.

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12 December 2020

Time course of the changes in prednisolone pharmacokinetics after co-administration or discontinuation of rifampin

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12 December 2020

10.2165/00003088-200342090-00003

Identifiers

DOI

1 reference

Dimensions Publication ID

7 August 2017

1014227941

0 references

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