(Q34123380)

31 July 2017

title

Small molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates (English)

1 reference

31 July 2017

Manfred Jung

4

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Wolfgang Sippl

object named as

Wolfgang Sippl

series ordinal

3

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author name string

Silviya D Furdas

series ordinal

1

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31 July 2017

Srinivasaraghavan Kannan

series ordinal

2

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31 July 2017

publication date

28 October 2011

1 reference

Archiv der Pharmazie - Chemistry in Life Sciences

31 July 2017

published in

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31 July 2017

volume

345

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31 July 2017

issue

1

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31 July 2017

page(s)

7-21

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Epigenetics: a historical overview

31 July 2017

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Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor

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MYST family histone acetyltransferases take center stage in stem cells and development.

21 January 2018

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Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

21 January 2018

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Steroid receptor coactivator-1 is a histone acetyltransferase

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Acetylation of histones and transcription-related factors

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.

21 January 2018

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21 January 2018

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Mice knock out for the histone acetyltransferase p300/CREB binding protein-associated factor develop a resistance to amyloid toxicity

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Induction of autophagy by spermidine promotes longevity

21 January 2018

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21 January 2018

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Selective HAT inhibitors as mechanistic tools for protein acetylation

21 January 2018

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21 January 2018

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Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer-specific chemo- and radiosensitization

21 January 2018

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Small molecule modulators of histone acetyltransferase p300.

21 January 2018

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Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of

21 January 2018

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Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation

21 January 2018

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21 January 2018

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Development of curcumin as an epigenetic agent

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Histone acetyltransferase inhibitors and preclinical studies

21 January 2018

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Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression

21 January 2018

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Mechanism of p300 specific histone acetyltransferase inhibition by small molecules

21 January 2018

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Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation

21 January 2018

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Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids

21 January 2018

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21 January 2018

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Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells

21 January 2018

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Characterization of novel inhibitors of histone acetyltransferases.

21 January 2018

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Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative

21 January 2018

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Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities

21 January 2018

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epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

21 January 2018

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Nitric oxide-mediated histone hyperacetylation in oral cancer: target for a water-soluble HAT inhibitor, CTK7A.

21 January 2018

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Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties

21 January 2018

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Design, synthesis, and biological evaluation of a small-molecule inhibitor of the histone acetyltransferase Gcn5.

21 January 2018

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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

21 January 2018

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Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase

21 January 2018

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Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones.

21 January 2018

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ICM?A new method for protein modeling and design: Applications to docking and structure prediction from the distorted native conformation

21 January 2018

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New anacardic acid-inspired benzamides: histone lysine acetyltransferase activators

21 January 2018

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The identification of a novel natural activator of p300 histone acetyltranferase provides new insights into the modulation mechanism of this enzyme.

21 January 2018

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Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases.

21 January 2018

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Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs).

21 January 2018

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Cinnamoyl Compounds as Simple Molecules that Inhibit p300 Histone Acetyltransferase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ARDP.201100209

1 reference

31 July 2017

1 reference