(Q34123413)

English

The BNIP-2 and Cdc42GAP homology (BCH) domain of p50RhoGAP/Cdc42GAP sequesters RhoA from inactivation by the adjacent GTPase-activating protein domain.

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8 February 2020

The BNIP-2 and Cdc42GAP homology (BCH) domain of p50RhoGAP/Cdc42GAP sequesters RhoA from inactivation by the adjacent GTPase-activating protein domain (English)

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8 February 2020

1

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8 February 2020

4

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8 February 2020

author name string

Li Li Chew

2

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8 February 2020

Sheng-cai Lin

3

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8 February 2020

publication date

21 July 2010

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8 February 2020

Molecular Biology of the Cell

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8 February 2020

21

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8 February 2020

18

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8 February 2020

3232-3246

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8 February 2020

Coordination of Rho and Rac GTPase function via p190B RhoGAP.

1 reference

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1 reference

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Nerve growth factor stimulates interaction of Cayman ataxia protein BNIP-H/Caytaxin with peptidyl-prolyl isomerase Pin1 in differentiating neurons

1 reference

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Rho GTPases in cancer cell biology

1 reference

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BNIP2 extra long inhibits RhoA and cellular transformation by Lbc RhoGEF via its BCH domain

1 reference

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Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

1 reference

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1 reference

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1 reference

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Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes

1 reference

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5 July 2018

Current knowledge of the large RhoGAP family of proteins

1 reference

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5 July 2018

Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels

1 reference

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Signaling during pathogen infection

1 reference

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5 July 2018

The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

Regulation of RhoGAP specificity by phospholipids and prenylation

1 reference

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5 July 2018

Sec14 homology domain targets p50RhoGAP to endosomes and provides a link between Rab and Rho GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

BNIP-Salpha induces cell rounding and apoptosis by displacing p50RhoGAP and facilitating RhoA activation via its unique motifs in the BNIP-2 and Cdc42GAP homology domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

Rho GTPases: biochemistry and biology

1 reference

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5 July 2018

Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment

1 reference

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5 July 2018

Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth

1 reference

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5 July 2018

RhoGDI: multiple functions in the regulation of Rho family GTPase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

GAPs in growth factor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

BNIP-2 induces cell elongation and membrane protrusions by interacting with Cdc42 via a unique Cdc42-binding motif within its BNIP-2 and Cdc42GAP homology domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis

1 reference

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5 July 2018

ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938388

5 July 2018

The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain

1 reference

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5 July 2018

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins

1 reference

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RHO-GTPases and cancer

1 reference

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1 reference

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Characterization of a brain-specific Rho GTPase-activating protein, p200RhoGAP

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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5 July 2018

The BNIP-2 and Cdc42GAP homology domain of BNIP-2 mediates its homophilic association and heterophilic interaction with Cdc42GAP

1 reference

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1 reference

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5 July 2018

Tyrosine phosphorylation of the Bcl-2-associated protein BNIP-2 by fibroblast growth factor receptor-1 prevents its binding to Cdc42GAP and Cdc42

1 reference

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Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

1 reference

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Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

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Rho GTPases and the actin cytoskeleton

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1 reference

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5 July 2018

The structure of the GTPase-activating domain from p50rhoGAP

1 reference

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RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG

1 reference

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1 reference

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1 reference

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rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo

1 reference

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1 reference

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1 reference

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1 reference

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Phospholipids can switch the GTPase substrate preference of a GTPase-activating protein

1 reference

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1 reference

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Characterization of the interaction between RhoGDI and Cdc42Hs using fluorescence spectroscopy.

1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20660160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E09-05-0408

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20660160%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20660160%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20660160%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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