(Q36707513)

15 August 2017

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title

Current knowledge of the large RhoGAP family of proteins (English)

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15 August 2017

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1

Joseph Tcherkezian

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15 August 2017

Nathalie Lamarche-Vane

series ordinal

2

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15 August 2017

1 February 2007

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15 August 2017

20

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based on heuristic

inferred from page(s)

published in

Biology of the Cell

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15 August 2017

99

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15 August 2017

2

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15 August 2017

67-86

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p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation.

15 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

A novel Rho GTPase-activating-protein interacts with Gem, a member of the Ras superfamily of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

ARHGAP10, a novel human gene coding for a potentially cytoskeletal Rho-GTPase activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Cloning, genomic organization and chromosomal assignment of the mouse p190-B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Rho and Rac take center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Phorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The Dbl family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

p115 Rho GTPase activating protein interacts with MEKK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Bcr encodes a GTPase-activating protein for p21rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Lowe syndrome protein OCRL1 interacts with Rac GTPase in the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Isolation of a novel human gene, ARHGAP9, encoding a rho-GTPase activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Identification and functional characterization of nadrin variants, a novel family of GTPase activating protein for rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Purification of ras GTPase activating protein from bovine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

SYD-1, a presynaptic protein with PDZ, C2 and rhoGAP-like domains, specifies axon identity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Nadrin, a novel neuron-specific GTPase-activating protein involved in regulated exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Structural organization of the bcr gene and its role in the Ph' translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Rho GTPases: biochemistry and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

A putative Xenopus Rho-GTPase activating protein (XrGAP) gene is expressed in the notochord and brain during the early embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Role of MgcRacGAP/Cyk4 as a regulator of the small GTPase Rho family in cytokinesis and cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The Dictyostelium Bcr/Abr-related protein DRG regulates both Rac- and Rab-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

p38 MAPK-mediated activation of NF-kappaB by the RhoGEF domain of Bcr.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

GAPs for rho-related GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Cloning and characterization of a rhoGAP homolog from Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

ARAP1: a point of convergence for Arf and Rho signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

A novel testicular RhoGAP-domain protein induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Characterization of a brain-specific Rho GTPase-activating protein, p200RhoGAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The rat myosin myr 5 is a GTPase-activating protein for Rho in vivo: essential role of arginine 1695

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

PARG1, a protein-tyrosine phosphatase-associated RhoGAP, as a putative Rap2 effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Role of the Rho GTPase-activating protein RICS in neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The Rac GTPase-activating protein RotundRacGAP interferes with Drac1 and Dcdc42 signalling in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Phosphorylation of the p190 RhoGAP N-terminal domain by c-Src results in a loss of GTP binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Dynamic expression of d-CdGAPr, a novel Drosophila melanogaster gene encoding a GTPase activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Cloning and characterization of a novel rho-type GTPase-activating protein gene (ARHGAP6) from the critical region for microphthalmia with linear skin defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The RHO1-GAPs SAC7, BEM2 and BAG7 control distinct RHO1 functions in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

ArhGAP15, a novel human RacGAP protein with GTPase binding property

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Association between GTPase activators for Rho and Ras families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

PKNbeta interacts with the SH3 domains of Graf and a novel Graf related protein, Graf2, which are GTPase activating proteins for Rho family

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

GTPase-activating proteins for Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

p190RhoGAP is cell cycle regulated and affects cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

p250GAP, a neural RhoGAP protein, is associated with and phosphorylated by Fyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Extracellular signal-regulated kinase 1 interacts with and phosphorylates CdGAP at an important regulatory site

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Rho GTPases and signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The Sequence of the Human Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Rho GTPase signaling in Dictyostelium discoideum: insights from the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

RA-RhoGAP, Rap-activated Rho GTPase-activating protein implicated in neurite outgrowth through Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Cloning and characterization of ARHGAP12, a novel human rhoGAP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

ARAP3 is a PI3K- and rap-regulated GAP for RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20060086

21 January 2018

Identifiers

DOI

10.1042/BC20060086

1 reference

release_us7blkkpofc4hnaojkgpf35p4y

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/us7blkkpofc4hnaojkgpf35p4y

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

17222083

1 reference

PubMed ID

17222083