(Q34123640)

English

The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Nicholas Brindle

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Harprit Singh

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Tania M Hansen

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Nisha Patel

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

0 references

publication date

3 January 2012

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

e29319

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

copyright license

Creative Commons Attribution 4.0 International

3 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Signaling and functions of angiopoietin-1 in vascular protection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Functional significance of Tie2 signaling in the adult vasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Phorbol 12-myristate 13-acetate-induced release of the colony-stimulating factor 1 receptor cytoplasmic domain into the cytosol involves two separate cleavage events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Not just angiogenesis--wider roles for the angiopoietins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Tie2 receptor expression is stimulated by hypoxia and proinflammatory cytokines in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Regulation of tie receptor expression on human endothelial cells by protein kinase C-mediated release of soluble tie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

TrkA receptor ectodomain cleavage generates a tyrosine-phosphorylated cell-associated fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

tie2, a putative protein tyrosine kinase from a new class of cell surface receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

5 July 2018

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029319

21 January 2018

Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029319

21 January 2018

Identification of a soluble form of the angiopoietin receptor TIE-2 released from endothelial cells and present in human blood

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029319

21 January 2018

An autocrine linkage between matrix metalloproteinase-14 and Tie-2 via ectodomain shedding modulates angiopoietin-1-dependent function in endothelial cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029319

21 January 2018

Vascular endothelial growth factor modulates the Tie-2:Tie-1 receptor complex.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029319

21 January 2018

Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029319

21 January 2018

Vascular endothelial growth factor activates the Tie family of receptor tyrosine kinases.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029319

21 January 2018

The ErbB-4 s80 intracellular domain is a constitutively active tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

28 October 2018

Transcriptional and post‐translation regulation of the Tiel receptor by fluid shear stress changes in vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

28 October 2018

The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

28 October 2018

Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250418

28 October 2018

Enhanced chemiluminescent method for the detection of DNA dot-hybridization assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential roles of metalloprotease mediated ectodomain cleavage in signaling by the endothelial receptor tyrosine kinase Tie-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory cytokines and vascular endothelial growth factor stimulate the release of soluble tie receptor from human endothelial cells via metalloprotease activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0029319

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

2012PLoSO...729319S

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235284%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34123640&oldid=1868405534"