(Q34126142)

31 July 2017

1 reference

title

Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors (English)

1 reference

G protein-coupled receptor

31 July 2017

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0 references

author name string

Pyne S

series ordinal

1

1 reference

PubMed ID

11150592

31 July 2017

Pyne N

series ordinal

2

1 reference

31 July 2017

1 November 2000

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Pharmacology & Therapeutics

31 July 2017

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31 July 2017

88

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31 July 2017

115-131

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31 July 2017

2

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Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Differential phospholipase D activation by bradykinin and sphingosine 1-phosphate in NIH 3T3 fibroblasts overexpressing gelsolin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Purification, characterization, and biosynthesis of human acid ceramidase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate stimulates tyrosine phosphorylation of Crk.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Mammalian lipid phosphate phosphohydrolases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Activation of muscarinic K+ current in guinea-pig atrial myocytes by sphingosine-1-phosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Regulation of phospholipase D.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Integrins and anoikis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Molecular cloning, tissue-specific expression, and chromosomal localization of a novel nerve growth factor-regulated G-protein- coupled receptor, nrg-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Effects of sphingosine 1-phosphate on pacemaker activity in rabbit sino-atrial node cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Cellular responses regulated by rho-related small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Ceramide in apoptosis--does it really matter?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Activation and translocation of Rho (and ADP ribosylation factor) by insulin in rat adipocytes. Apparent involvement of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Molecular cloning and functional characterization of murine sphingosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Ceramide and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Comparison of intrinsic activities of the putative sphingosine 1-phosphate receptor subtypes to regulate several signaling pathways in their cDNA-transfected Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate induces heat shock protein 27 via p38 mitogen-activated protein kinase activation in osteoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Signalling sphingomyelinases: which, where, how and why?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

A putative G-protein-coupled receptor, H218, is down-regulated during the retinoic acid-induced differentiation of F9 embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

1 reference

7 January 2021

Cloning and characterization of a putative G-protein coupled receptor potentially involved in development

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Signal transduction of stress via ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Receptor-mediated activation of phospholipase D by sphingosine 1-phosphate in skeletal muscle C2C12 cells. A role for protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Bioactive lysophospholipids and their G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Purification and characterization of rat kidney sphingosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

The role of ceramide in cell signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

The differential regulation of cyclic AMP by sphingomyelin-derived lipids and the modulation of sphingolipid-stimulated extracellular signal regulated kinase-2 in airway smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Evidence that lipoproteins are carriers of bioactive factors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Exogenous sphingosine 1-phosphate induces neurite retraction possibly through a cell surface receptor in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine-1-phosphate mobilizes intracellular calcium and activates transcription factor NF-kappa B in U937 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Distribution and properties of dihydrosphingosine-1-phosphate aldolase (sphinganine-1-phosphate alkanal-lyase).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Ceramidase and ceramide synthesis in human kidney and cerebellum. Description of a new alkaline ceramidase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate mobilizes sequestered calcium, activates calcium entry, and stimulates deoxyribonucleic acid synthesis in thyroid FRTL-5 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphinganine 1-phosphate metabolism in cultured skin fibroblasts: evidence for the existence of a sphingosine phosphatase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Activation of protein-tyrosine kinase Syk in human platelets stimulated with lysophosphatidic acid or sphingosine 1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Metabolism and functional effects of sphingolipids in blood cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900084-X

7 January 2021

10.1016/S0163-7258(00)00084-X

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11150592