(Q34131040)

31 July 2017

Endogenous interleukin-12 is critical for controlling the late but not the early stage of Leishmania mexicana infection in C57BL/6 mice (English)

1 reference

31 July 2017

Leishmania mexicana

1 reference

Eric Muraille

5

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author name string

Fabiola Aguilar Torrentera

1

1 reference

31 July 2017

Jon D Laman

2

1 reference

31 July 2017

Marjan Van Meurs

3

1 reference

31 July 2017

Luciano Adorini

4

1 reference

31 July 2017

Y Carlier

6

1 reference

31 July 2017

language of work or name

English

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publication date

1 September 2002

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31 July 2017

Infection and Immunity

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31 July 2017

70

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31 July 2017

9

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31 July 2017

5075-5080

1 reference

Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Regulation of interleukin-12 production in antigen-presenting cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

T-cell responses to immunodominant LACK antigen do not play a critical role in determining susceptibility of BALB/c mice to Leishmania mexicana

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

The biogenesis and properties of the parasitophorous vacuoles that harbour Leishmania in murine macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Course of Leishmania infection in beta 2-microglobulin-deficient mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

The regulation of immunity to Leishmania major

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Altered immune responses in mice lacking inducible nitric oxide synthase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Incidence of localized cutaneous leishmaniasis (chiclero's ulcer) in Mexico

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

In vitro indomethacin administration upregulates interleukin-12 production and polarizes the immune response towards a Th1 type in susceptible BALB/c mice infected with Leishmania mexicana.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Susceptibility to Leishmania mexicana infection is due to the inability to produce IL-12 rather than lack of IL-12 responsiveness.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Rapid early onset lymphocyte cell death in mice resistant, but not susceptible to Leishmania major infection

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

IL-12 is required to maintain a Th1 response during Leishmania major infection.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

SCID mice reconstituted with IL-4-deficient lymphocytes, but not immunocompetent lymphocytes, are resistant to cutaneous leishmaniasis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

Diffuse cutaneous leishmaniasis in Mexico

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128289

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection

28 October 2018

1 reference

12 December 2020

The development of a Th1-type response and resistance to Leishmania major infection in the absence of CD40-CD40L costimulation

1 reference

12 December 2020

Parasitic load and histopathology of cutaneous lesions, lymph node, spleen, and liver from BALB/c and C57BL/6 mice infected with Leishmania mexicana

1 reference

12 December 2020

IL-12 receptor regulation in IL-12-deficient BALB/c and C57BL/6 mice

1 reference

12 December 2020

Genetically resistant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection

1 reference

12 December 2020

IL-4-independent inhibition of IL-12 responsiveness during Leishmania amazonensis infection

1 reference

12 December 2020

Maintenance of IL-12-responsive CD4+ T cells during a Th2 response in Leishmania major-infected mice

1 reference

12 December 2020

Silent infection of bone marrow-derived dendritic cells byLeishmania mexicana amastigotes

1 reference

12 December 2020

BALB/c mice bearing a transgenic IL-12 receptor beta 2 gene exhibit a nonhealing phenotype to Leishmania major infection despite intact IL-12 signaling

1 reference

12 December 2020

The clinical and immunological spectrum of American cutaneous leishmaniasis

1 reference

12 December 2020

IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis

1 reference

12 December 2020

Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity

1 reference

12 December 2020

CD40 ligand is required for protective cell-mediated immunity to Leishmania major

1 reference

12 December 2020

Mice lacking the TNF receptor p55 fail to resolve lesions caused by infection with Leishmania major, but control parasite replication

1 reference

12 December 2020

The resolution of lesions induced by Leishmania major in mice requires a functional Fas (APO-1, CD95) pathway of cytotoxicity

1 reference

12 December 2020

Phagocytosis of Leishmania mexicana amastigotes by macrophages leads to a sustained suppression of IL-12 production

1 reference

12 December 2020

IL-10 enhances NK cell proliferation, cytotoxicity and production of IFN-gamma when combined with IL-18

1 reference

12 December 2020

10.1128/IAI.70.9.5075-5080.2002

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference