(Q34135439)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

review article

1 reference

title

The beta-globin locus control region versus gene therapy vectors: a struggle for expression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

D Pannell

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

publication date

1 January 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

17-24

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro

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Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control region

21 January 2018

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Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching

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Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus.

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Activation by locus control regions?

21 January 2018

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Transcription complex stability and chromatin dynamics in vivo

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The effect of distance on long-range chromatin interactions

21 January 2018

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Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

21 January 2018

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Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice

21 January 2018

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The complexities of beta globin gene regulation

21 January 2018

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The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells

21 January 2018

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The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus.

21 January 2018

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Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes

21 January 2018

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Looping versus linking: toward a model for long-distance gene activation

21 January 2018

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Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector

21 January 2018

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Lineage-specific expression of a human beta-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A chromatin insulator protects retrovirus vectors from chromosomal position effects

21 January 2018

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21 January 2018

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21 January 2018

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Methylation-induced repression--belts, braces, and chromatin

21 January 2018

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High-resolution analysis of cytosine methylation in the 5ĺong terminal repeat of retroviral vectors

21 January 2018

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Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells

21 January 2018

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De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells

21 January 2018

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Independent mechanisms involved in suppression of the Moloney leukemia virus genome during differentiation of murine teratocarcinoma cells

21 January 2018

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Dynamic analysis of proviral induction and De Novo methylation: implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression

21 January 2018

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Retroviral transfer of a human beta-globin/delta-globin hybrid gene linked to beta locus control region hypersensitive site 2 aimed at the gene therapy of sickle cell disease

21 January 2018

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Genetic correction of sickle cell disease: insights using transgenic mouse models

21 January 2018

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Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells

21 January 2018

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Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy

21 January 2018

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Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols.

21 January 2018

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Delayed de novo methylation in teratocarcinoma suggests additional tissue-specific mechanisms for controlling gene expression

21 January 2018

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The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region.

21 January 2018

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7 January 2021

Detailed analysis of the site 3 region of the human beta-globin dominant control region

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7 January 2021

Synthetic human beta-globin 5'HS2 constructs function as locus control regions only in multicopy transgene concatamers.

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7 January 2021

Do LCRs open chromatin domains?

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7 January 2021

Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure

1 reference

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7 January 2021

Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2001.590103.X

7 January 2021

Increased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells

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7 January 2021

Knockout-transgenic mouse model of sickle cell disease

1 reference

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7 January 2021

10.1034/J.1399-0004.2001.590103.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11168020%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference