(Q34138135)

31 July 2017

title

First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay (English)

1 reference

31 July 2017

1 reference

Jean Rosenbaum

7

1 reference

ORCID Public Data File 2021

author name string

Judith Elkaim

1

1 reference

31 July 2017

Michel Castroviejo

2

1 reference

31 July 2017

Driss Bennani

3

1 reference

31 July 2017

Said Taouji

4

1 reference

31 July 2017

Nathalie Allain

5

1 reference

31 July 2017

Michel Laguerre

6

1 reference

31 July 2017

Jean Dessolin

8

1 reference

31 July 2017

Patrick Lestienne

9

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 April 2012

1 reference

31 July 2017

1 reference

31 July 2017

volume

443

1 reference

31 July 2017

issue

2

1 reference

31 July 2017

page(s)

549-559

1 reference

Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Biochemical properties of RuvBD113N: a mutation in helicase motif II of the RuvB hexamer affects DNA binding and ATPase activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Crystal structure of the human AAA+ protein RuvBL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Classification of AAA+ proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Dodecameric structure and ATPase activity of the human TIP48/TIP49 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

RVB1/RVB2: running rings around molecular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

A chromatin remodelling complex involved in transcription and DNA processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Control of transcription by Pontin and Reptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

The Saccharomyces cerevisiae RuvB-like protein, Tih2p, is required for cell cycle progression and RNA polymerase II-directed transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

TIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

An eukaryotic RuvB-like protein (RUVBL1) essential for growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Cooperative action of TIP48 and TIP49 in H2A.Z exchange catalyzed by acetylation of nucleosomal H2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

DrugScore(CSD)-knowledge-based scoring function derived from small molecule crystal data with superior recognition rate of near-native ligand poses and better affinity prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Knowledge-based scoring function to predict protein-ligand interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Further development and validation of empirical scoring functions for structure-based binding affinity prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Open Babel: An open chemical toolbox

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Virtual screening for HIV protease inhibitors: a comparison of AutoDock 4 and Vina

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

The Blue Obelisk-interoperability in chemical informatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Consensus scoring: A method for obtaining improved hit rates from docking databases of three-dimensional structures into proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

TIP49b, a new RuvB-like DNA helicase, is included in a complex together with another RuvB-like DNA helicase, TIP49a

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

A rat RuvB-like protein, TIP49a, is a germ cell-enriched novel DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Reptin and pontin antagonistically regulate heart growth in zebrafish embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Direct evidence that a conserved arginine in RuvB AAA+ ATPase acts as an allosteric effector for the ATPase activity of the adjacent subunit in a hexamer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

Intersubunit coordination in a homomeric ring ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

How does consensus scoring work for virtual library screening? An idealized computer experiment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111779

21 January 2018

Identifiers

DOI

10.1042/BJ20111779

1 reference

31 July 2017

1 reference