(Q34138219)

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5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585.

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585. (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

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author name string

Simon Z East

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

Philip W J Burnet

2

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31 July 2017

Ronald A Leslie

3

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31 July 2017

Jennifer C Roberts

4

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31 July 2017

Paul J Harrison

5

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31 July 2017

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1 September 2002

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Europe PubMed Central

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31 July 2017

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31 July 2017

45

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31 July 2017

3

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31 July 2017

191-199

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31 July 2017

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A review of central 5-HT receptors and their function

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Pre- and postmortem influences on brain RNA.

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5-ht6 receptors as emerging targets for drug discovery

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5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia.

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[3H]WAYâ 100635 for 5â HT1A receptor autoradiography in human brain: a comparison with [3H]8â OHâ DPAT and demonstration of increased binding in the frontal cortex in schizophrenia

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Potent antagonism of 5-HT(3) and 5-HT(6) receptors by olanzapine

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In vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate

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The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus

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Characterization of [(125)I]-SB-258585 binding to human recombinant and native 5-HT(6) receptors in rat, pig and human brain tissue

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Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics

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Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor

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Serotonergic basis of antipsychotic drug effects in schizophrenia.

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Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia

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The role of serotonin in antipsychotic drug action

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Effects of the 5-HT(6) receptor antagonist Ro 04-6790 on learning consolidation

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Anxiogenic-like effects and reduced stereological counting of immunolabelled 5-hydroxytryptamine6 receptors in rat nucleus accumbens by antisense oligonucleotides

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The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585.

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5-HT6 receptor antagonists enhance retention of a water maze task in the rat.

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A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation

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5-Hydroxytryptamine receptors with a 5-HT6 receptor-like profile stimulating adenylyl cyclase activity in pig caudate membranes

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Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors

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Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry

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Prefrontal function in schizophrenia: confounds and controversies

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A role for 5-ht6 receptors in retention of spatial learning in the Morris water maze.

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Impact of adrenalectomy on 5-HT6 and 5-HT7 receptor gene expression in the rat hippocampus.

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Autoradiography with [3H]8-OH-DPAT reveals increases in 5-HT1A receptors in ventral prefrontal cortex in schizophrenia

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Identifiers

10.1002/SYN.10097

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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