(Q34139321)

31 July 2017

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title

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. (English)

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31 July 2017

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1

Korsmeyer SJ

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31 July 2017

Wei MC

2

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31 July 2017

Saito M

3

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31 July 2017

Weiler S

4

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31 July 2017

Oh KJ

5

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31 July 2017

Schlesinger PH

6

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31 July 2017

1 December 2000

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Cell Death & Differentiation

31 July 2017

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31 July 2017

7

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31 July 2017

1166-1173

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31 July 2017

12

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400783

31 July 2017

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cites work

Mitochondria and apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Caspases: enemies within

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bcl-2-family proteins: the role of the BH3 domain in apoptosis.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Solution structure of BID, an intracellular amplifier of apoptotic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Regulated targeting of BAX to mitochondria.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

BID: a novel BH3 domain-only death agonist

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Ion channel activity of the BH3 only Bcl-2 family member, BID.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Inhibition of Bax channel-forming activity by Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Signal transduction by allosteric receptor oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

BAX-dependent transport of cytochrome c reconstituted in pure liposomes

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Lethal effect of the anti-Fas antibody in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Pharmacological modifications of the sodium channels of frog nerve

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400783

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400783

1 reference

31 July 2017

1 reference