(Q34140173)

31 July 2017

title

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders (English)

1 reference

Vesicle-associated membrane protein 7

31 July 2017

main subject

1 reference

Vesicle transport through interaction with t-SNAREs homolog 1B

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Fabio Annunziata

2

0 references

Alessia Lombardi

Alessia Lombardi

3

0 references

Diego Luis Medina

Diego Luis Medina

5

0 references

Andrea Ballabio

Andrea Ballabio

11

0 references

Kai Simons

Kai Simons

10

0 references

author name string

Alessandro Fraldi

1

1 reference

31 July 2017

Hermann-Josef Kaiser

4

1 reference

31 July 2017

Carmine Spampanato

6

1 reference

31 July 2017

Anthony Olind Fedele

7

1 reference

31 July 2017

Roman Polishchuk

8

1 reference

31 July 2017

Nicolina Cristina Sorrentino

9

1 reference

31 July 2017

language of work or name

English

0 references

publication date

24 September 2010

1 reference

31 July 2017

1 reference

31 July 2017

volume

29

1 reference

31 July 2017

issue

21

1 reference

31 July 2017

page(s)

3607-3620

1 reference

describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2982760/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Lipid rafts as a membrane-organizing principle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Order of lipid phases in model and plasma membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

A gene network regulating lysosomal biogenesis and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Rab7: roles in membrane trafficking and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Secondary lipid accumulation in lysosomal disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

A novel site of action for alpha-SNAP in the SNARE conformational cycle controlling membrane fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

A block of autophagy in lysosomal storage disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Lysosomes: fusion and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

SNARE proteins and 'membrane rafts'.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

VAMP4 cycles from the cell surface to the trans-Golgi network via sorting and recycling endosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Cholesterol dysfunction in neurodegenerative diseases: is Huntington's disease in the list?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

SNAREs--engines for membrane fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Lipid raft association of SNARE proteins regulates exocytosis in PC12 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Lipid rafts and membrane dynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

EpsinR is an adaptor for the SNARE protein Vti1b

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Elevated endosomal cholesterol levels in Niemann-Pick cells inhibit rab4 and perturb membrane recycling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Model systems, lipid rafts, and cell membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Elevated lysosomal pH in neuronal ceroid lipofuscinoses (NCLs)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

SNARE-complex disassembly by NSF follows synaptic-vesicle fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

SNAREpins: minimal machinery for membrane fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Functional rafts in cell membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2982760

Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

Detergent resistance as a tool in membrane research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

Ternary SNARE complexes are enriched in lipid rafts during mast cell exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

Jamming the endosomal system: lipid rafts and lysosomal storage diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

Role of lipid microdomains in P/Q-type calcium channel (Cav2.1) clustering and function in presynaptic membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

Synaptic core complex of synaptobrevin, syntaxin, and SNAP25 forms high affinity alpha-SNAP binding site

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20871593

12 December 2020

inferred from PubMed ID database lookup

Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20871593

12 December 2020

inferred from PubMed ID database lookup

Overexpression of epsilon-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.237

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/EMBOJ.2010.237

1 reference

31 July 2017

1 reference

31 July 2017

1 reference