(Q34140652)

31 July 2017

title

Gene optimization is necessary to express a bivalent anti-human anti-T cell immunotoxin in Pichia pastoris (English)

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31 July 2017

Pichia pastoris

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Jung Hee Woo

1

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31 July 2017

Yuan Yi Liu

2

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31 July 2017

Askale Mathias

3

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31 July 2017

Scott Stavrou

4

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31 July 2017

Zhirui Wang

5

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31 July 2017

Jerry Thompson

6

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31 July 2017

David M Neville

7

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31 July 2017

publication date

1 July 2002

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Protein Expression and Purification

31 July 2017

published in

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31 July 2017

volume

25

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31 July 2017

issue

2

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31 July 2017

page(s)

270-282

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Durable donor-specific T and B cell tolerance in rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin: absence of chronic allograft nephropathy

31 July 2017

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In vivo T-cell ablation by a holo-immunotoxin directed at human CD3

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A new reagent for the induction of T-cell depletion, anti-CD3-CRM9.

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7 January 2021

Improved binding of a bivalent single-chain immunotoxin results in increased efficacy for in vivo T-cell depletion

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7 January 2021

An anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin avoids inhibition by pre-existing antibodies in human blood

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Influence of relative binding affinity on efficacy in a panel of anti-CD3 scFv immunotoxins

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7 January 2021

Expression of an anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin in a mutant CHO cell line

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One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell

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Cloned diphtheria toxin within the periplasm of Escherichia coli causes lethal membrane damage at low pH.

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Saccharomyces cerevisiae spheroplasts are sensitive to the action of diphtheria toxin

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7 January 2021

Heterologous protein production in methylotrophic yeasts

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7 January 2021

Expression of tetanus toxin fragment C in yeast: gene synthesis is required to eliminate fortuitous polyadenylation sites in AT-rich DNA.

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7 January 2021

Fermentation, Purification, and Efficacy of a Recombinant Vaccine Candidate against Botulinum Neurotoxin Type F from Pichia pastoris

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7 January 2021

Codon optimization markedly improves doxycycline regulated gene expression in the mouse heart

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7 January 2021

High-level expression in mammalian cells of recombinant house dust mite allergen ProDer p 1 with optimized codon usage

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7 January 2021

High-level periplasmic expression in Escherichia coli using a eukaryotic signal peptide: importance of codon usage at the 5' end of the coding sequence

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7 January 2021

Codon optimization of xylanase gene xynB from the thermophilic bacterium Dictyoglomus thermophilum for expression in the filamentous fungus Trichoderma reesei

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7 January 2021

Expression of diphtheria toxin fragment A and hormone-toxin fusion proteins in toxin-resistant yeast mutants

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7 January 2021

A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1 beta in Saccharomyces cerevisiae.

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7 January 2021

Efficient secretion and processing of heterologous proteins in Saccharomyces cerevisiae is mediated solely by the pre-segment of alpha-factor precursor

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7 January 2021

Diphtheria toxin entry into cells is facilitated by low pH.

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7 January 2021

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement

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7 January 2021

On the interaction between single chain Fv antibodies and bacterial immunoglobulin-binding proteins.

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7 January 2021

NMR analysis of the interaction between protein L and Ig light chains

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7 January 2021

Generation of a recombinant chimeric Newcastle disease virus vaccine that allows serological differentiation between vaccinated and infected animals

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7 January 2021

Production of functionalized single-chain Fv antibody fragments binding to the ED-B domain of the B-isoform of fibronectin in Pichia pastoris

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7 January 2021

Secreted production of a custom-designed, highly hydrophilic gelatin in Pichia pastoris

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7 January 2021

Human insulin from a precursor overexpressed in the methylotrophic yeast Pichia pastoris and a simple procedure for purifying the expression product

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7 January 2021

Disruption of the KEX1 gene in Pichia pastoris allows expression of full-length murine and human endostatin

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7 January 2021

Expression of non-ADP-ribosylatable, diphtheria toxin-resistant elongation factor 2 in Saccharomyces cerevisiae

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7 January 2021

Identification of a stem-loop structure important for polyadenylation at the murine IgM secretory poly(A) site

1 reference

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7 January 2021

10.1016/S1046-5928(02)00009-8

Identifiers

DOI

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31 July 2017

1 reference