(Q34145063)

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Constraining binding hot spots: NMR and molecular dynamics simulations provide a structural explanation for enthalpy-entropy compensation in SH2-ligand binding

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Europe PubMed Central

PubMed publication ID

31 July 2017

Constraining binding hot spots: NMR and molecular dynamics simulations provide a structural explanation for enthalpy-entropy compensation in SH2-ligand binding (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Joshua M Ward

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Nina M Gorenstein

2

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Europe PubMed Central

PubMed publication ID

31 July 2017

Jianhua Tian

3

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Europe PubMed Central

PubMed publication ID

31 July 2017

Stephen F Martin

4

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Europe PubMed Central

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31 July 2017

Carol Beth Post

5

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Europe PubMed Central

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31 July 2017

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publication date

1 August 2010

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Europe PubMed Central

PubMed publication ID

31 July 2017

Journal of the American Chemical Society

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Europe PubMed Central

PubMed publication ID

31 July 2017

132

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Europe PubMed Central

PubMed publication ID

31 July 2017

32

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Europe PubMed Central

PubMed publication ID

31 July 2017

11058-11070

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

All-atom empirical potential for molecular modeling and dynamics studies of proteins

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Win some, lose some: enthalpy-entropy compensation in weak intermolecular interactions

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pH titration studies of an SH2 domain-phosphopeptide complex: unusual histidine and phosphate pKa values.

1 reference

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1 reference

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Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode

1 reference

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1 reference

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1 reference

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1 reference

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Protein dynamics from NMR

1 reference

https://pubmed.ncbi.nlm.nih.gov/20698672

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based on heuristic

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Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20698672

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Mutational investigation of the specificity determining region of the Src SH2 domain

1 reference

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based on heuristic

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Identifiers

10.1021/JA910535J

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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