(Q34145670)

31 July 2017

title

A general chemical method to regulate protein stability in the mammalian central nervous system (English)

1 reference

31 July 2017

0 references

Mari Iwamoto

1

1 reference

31 July 2017

Tomas Björklund

2

1 reference

31 July 2017

Cecilia Lundberg

3

1 reference

31 July 2017

Deniz Kirik

4

1 reference

31 July 2017

Thomas J Wandless

5

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31 July 2017

publication date

1 September 2010

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31 July 2017

published in

Chemistry and Biology

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31 July 2017

volume

17

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31 July 2017

issue

9

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31 July 2017

page(s)

981-988

1 reference

A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes

31 July 2017

cites work

1 reference

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An auxin-based degron system for the rapid depletion of proteins in nonplant cells.

5 July 2018

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Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants

5 July 2018

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A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Specific recognition and cleavage of the plus-strand primer by reverse transcriptase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Detecting protein-protein interactions with a green fluorescent protein fragment reassembly trap: scope and mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Structure, dynamics, and catalytic function of dihydrofolate reductase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

siRNA-mediated gene silencing in vitro and in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Distribution and elimination of trimethoprim in pregnant and newborn rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Dihydrofolate reductase as a therapeutic target

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

The function of amino acid residues contacting the nicotinamide ring of NADPH in dihydrofolate reductase from Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

The penetration of antibiotics into cerebrospinal fluid and brain tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Chemical control of protein stability and function in living mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Rapid control of protein level in the apicomplexan Toxoplasma gondii

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Conditional protein alleles using knockin mice and a chemical inducer of dimerization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

A cytomegalovirus glycoprotein re-routes MHC class I complexes to lysosomes for degradation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Analysis of a conditional degradation signal in yeast and mammalian cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Heat-inducible degron: a method for constructing temperature-sensitive mutants.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943492

Intravenous safety and pharmacokinetics of a novel dimerizer drug, AP1903, in healthy volunteers

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20851347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dihydrofolate reductase. The stereochemistry of inhibitor selectivity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20851347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20851347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CHEMBIOL.2010.07.009

1 reference

31 July 2017

1 reference

31 July 2017

1 reference