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CD20-induced B cell death can bypass mitochondria and caspase activation.
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
title
CD20-induced B cell death can bypass mitochondria and caspase activation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
mitochondrion
1 reference
based on heuristic
inferred from title
cell death
1 reference
based on heuristic
inferred from title
author
Rene van Lier
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
van der Kolk LE
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Evers LM
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Omene C
series ordinal
3
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Lens SM
series ordinal
4
1 reference
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Lederman S
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
van Oers MH
series ordinal
7
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Eldering E
series ordinal
8
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
publication date
1 September 2002
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Leukemia
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
16
1 reference
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
9
1 reference
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Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
1735-1744
1 reference
stated in
Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.leu.2402559
0 references
cites work
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.
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Single-agent monoclonal antibody efficacy in bulky non-Hodgkin's lymphoma: results of a phase II trial of rituximab
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Clustered CD20 induced apoptosis: src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis
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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
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Apoptosis signaling
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Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts
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The biochemistry of apoptosis
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Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?
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Crossref
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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
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Two CD95 (APO-1/Fas) signaling pathways
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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
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Crossref
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7 January 2021
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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
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7 January 2021
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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
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CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia
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PML induces a novel caspase-independent death process
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Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.
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Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
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Measurement of protein using bicinchoninic acid
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Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.
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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
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Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.
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Crossref
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Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
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Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells
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Ligation of major histocompatability complex (MHC) class I molecules on human T cells induces cell death through PI-3 kinase-induced c-Jun NH2-terminal kinase activity: a novel apoptotic pathway distinct from Fas-induced apoptosis
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Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis
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Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta
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Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species
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Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin.
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Identifiers
DOI
10.1038/SJ.LEU.2402559
1 reference
stated in
Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Dimensions Publication ID
1009467445
0 references
PubMed ID
12200688
1 reference
stated in
Europe PubMed Central
PubMed ID
12200688
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200688%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
ResearchGate publication ID
11187204
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