(Q34153277)

31 July 2017

title

Amifostine: mechanisms of action underlying cytoprotection and chemoprevention (English)

1 reference

31 July 2017

1 reference

ChEBI release 2020-05-28

Grdina DJ

1

1 reference

31 July 2017

Kataoka Y

series ordinal

2

1 reference

31 July 2017

Murley JS

series ordinal

3

1 reference

31 July 2017

publication date

1 January 2000

1 reference

Drug Metabolism and Drug Interactions

31 July 2017

published in

1 reference

31 July 2017

volume

16

1 reference

31 July 2017

issue

4

1 reference

31 July 2017

page(s)

237-279

1 reference

Amifostine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential as a radioprotector and cytotoxic chemoprotector

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Radioprotection by WR-2721 of gamma-irradiated rat parotid gland: effect on gland weight and secretion at 8-10 days post irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Redox competition and radiosensitivity: implications for testing radioprotective compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Mechanism of the radioprotecting action of chemical compounds on Escherichia coli cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Radiation protection of E. coli strains by cysteamine in the presence of oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Cancer chemoprevention: principles and prospects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

In vivo effects of N-acetylcysteine on glutathione metabolism and on the biotransformation of carcinogenic and/or mutagenic compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

The radioprotector WR1065 reduces radiation-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in V79 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

2-[(Aminopropyl)amino]ethanethiol (WR1065) is anti-neoplastic and anti-mutagenic when given during 60Co gamma-ray irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Effects of WR-1065 and WR-151326 on survival and neoplastic transformation in C3H/10T1/2 cells exposed to TRIGA or JANUS fission neutrons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

In vivo protection by the aminothiol WR-2721 against neutron-induced carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Role of oxidants and antioxidants in the induction of AP-1, NF-kappaB, and glutathione S-transferase gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Redox control of enzyme activities by thiol/disulfide exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Redox signaling and the emerging therapeutic potential of thiol antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Oltipraz stimulates the transcription of the manganese superoxide dismutase gene in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

The cytoprotective aminothiol WR1065 activates p21waf-1 and down regulates cell cycle progression through a p53-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Experimental chelation therapy in chromium, lead, and boron intoxication with N-acetylcysteine and other compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Protection from cellular oxidative injury and calcium intrusion by N-(2-mercaptoethyl)-1,3-propanediamine, WR 1065.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Matrix metalloproteinases and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Competition for polyamine uptake into rat lung slices by WR2721 and analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Involvement of the polyamine transport system in cellular uptake of the radioprotectants WR-1065 and WR-33278.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Conformational changes in chromatin structure induced by the radioprotective aminothiol, WR 1065

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

The effect of 2-[(aminopropyl)amino] ethanethiol on fission-neutron-induced DNA damage and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Effects of radioprotectors on DNA damage and repair, proteins, and cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Mechanism of Action of Aminothiol Radioprotectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

Chemopreventive properties and mechanisms of N-Acetylcysteine. The experimental background

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2000.16.4.237

10.1515/DMDI.2000.16.4.237

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference