(Q34153309)

31 July 2017

title

Simvastatin attenuates ventilator-induced lung injury in mice (English)

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31 July 2017

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12

Martin Witzenrath

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31 July 2017

Norbert Suttorp

11

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ORCID Public Data File 2021

Stefan Hippenstiel

8

object named as

Stefan Hippenstiel

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31 July 2017

7

Bernd Schmeck

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31 July 2017

Holger C Müller

1

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31 July 2017

Katharina Hellwig

2

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31 July 2017

Simone Rosseau

3

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31 July 2017

Thomas Tschernig

4

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31 July 2017

Andreas Schmiedl

5

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31 July 2017

Birgitt Gutbier

6

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31 July 2017

Harm Peters

9

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31 July 2017

Lars Morawietz

10

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31 July 2017

publication date

30 July 2010

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31 July 2017

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31 July 2017

volume

14

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31 July 2017

issue

4

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31 July 2017

page(s)

R143

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Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers

31 July 2017

cites work

1 reference

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Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition

5 July 2018

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Animal models of acute lung injury

5 July 2018

1 reference

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The effect of simvastatin on the serum monocyte chemoattractant protein-1 and intracellular adhesion molecule-1 levels in diabetic rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Lung protective ventilatory strategies in acute lung injury and acute respiratory distress syndrome: from experimental findings to clinical application

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction

5 July 2018

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Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome

5 July 2018

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Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Pretreatment with simvastatin reduces lung injury related to intestinal ischemia-reperfusion in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

HMG CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation

5 July 2018

1 reference

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Statin-inhibited endothelial permeability could be associated with its effect on PECAM-1 in endothelial cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

5 July 2018

1 reference

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Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial

5 July 2018

1 reference

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Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome

5 July 2018

1 reference

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Effect of granulocyte depletion in a ventilated surfactant-depleted lung

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Pitavastatin prevents intestinal ischemia/reperfusion-induced bacterial translocation and lung injury in atherosclerotic rats with hypoadiponectinemia

5 July 2018

1 reference

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Role of lung-marginated monocytes in an in vivo mouse model of ventilator-induced lung injury

28 October 2018

1 reference

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Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice

28 October 2018

1 reference

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Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29,900 patients

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Simvastatin suppresses lung inflammatory response in a rat cardiopulmonary bypass model

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Protection from experimental ventilator-induced acute lung injury by IL-1 receptor blockade.

28 October 2018

1 reference

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Effectiveness of statins in reducing the rate of severe sepsis: a retrospective evaluation.

28 October 2018

1 reference

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Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model.

28 October 2018

1 reference

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Neutrophil stimulation with granulocyte colony-stimulating factor worsens ventilator-induced lung injury and mortality in rats

28 October 2018

1 reference

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The concept of "baby lung".

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Simvastatin modulates TNFalpha-induced adhesion molecules expression in human endothelial cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma

28 October 2018

1 reference

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Apoptosis and necrosis induced by cyclic mechanical stretching in alveolar type II cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Simvastatin ameliorates injury in an experimental model of lung ischemia-reperfusion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Simvastatin inhibits inflammatory properties of Staphylococcus aureus alpha-toxin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945124

Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia

28 October 2018

1 reference

12 December 2020

Effects of simvastatin in abdominal sepsis in rats

1 reference

12 December 2020

Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings

1 reference

12 December 2020

Impact of statins and angiotensin-converting enzyme inhibitors on mortality of subjects hospitalised with pneumonia

1 reference

12 December 2020

Effects of respiratory rate on ventilator-induced lung injury at a constant PaCO2 in a mouse model of normal lung

1 reference

12 December 2020

Statin administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC9209

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Dimensions Publication ID

31 July 2017

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31 July 2017

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