(Q34154195)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis (English)

1 reference

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18 January 2020

1

1 reference

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18 January 2020

Duncan B. Sparrow

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Sally L. Dunwoodie

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Elisabeth Kremmer

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

7 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

20

1 reference

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18 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

905-916

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147753%20AND%20SRC:MED&resulttype=core&format=json

Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Mutated MESP2 causes spondylocostal dysostosis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Identification of oscillatory genes in somitogenesis from functional genomic analysis of a human mesenchymal stem cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Disruption of the somitic molecular clock causes abnormal vertebral segmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

A complex oscillating network of signaling genes underlies the mouse segmentation clock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Notch signalling synchronizes the zebrafish segmentation clock but is not needed to create somite boundaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Notch signalling and the synchronization of the somite segmentation clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Dll3 pudgy mutation differentially disrupts dynamic expression of somite genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

O-fucosylation of notch occurs in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The Notch1 receptor is cleaved constitutively by a furin-like convertase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Fringe is a glycosyltransferase that modifies Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Signalling downstream of activated mammalian Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Numb regulates post-endocytic trafficking and degradation of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

AIP4/Itch regulates Notch receptor degradation in the absence of ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Imaging and imagination: understanding the endo-lysosomal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Intracellular cell-autonomous association of Notch and its ligands: a novel mechanism of Notch signal modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

A nomenclature for prospective somites and phases of cyclic gene expression in the presomitic mesoderm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The many facets of Notch ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Cell and molecular biology of Notch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Plasticity of the differentiated state

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Ligand-induced signaling in the absence of furin processing of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Progressive spatial restriction of Sek-1 and Krox-20 gene expression during hindbrain segmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Notch1 is essential for postimplantation development in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Notch signalling: a simple pathway becomes complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

The role of Notch in patterning the human vertebral column

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

High levels of Notch signaling down-regulate Numb and Numblike

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529

Expression analysis of a Notch homologue in the mouse embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ529