(Q34156274)

31 July 2017

title

Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity (English)

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31 July 2017

Naoyuki Yabana

1

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31 July 2017

Masabumi Shibuya

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 October 2002

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31 July 2017

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31 July 2017

volume

21

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31 July 2017

issue

50

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31 July 2017

page(s)

7720-7729

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Vav2 is an activator of Cdc42, Rac1, and RhoA

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Involvement of NH(2)-terminal sequences in the negative regulation of Vav signaling and transforming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Galpha 13 requires palmitoylation for plasma membrane localization, Rho-dependent signaling, and promotion of p115-RhoGEF membrane binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Autoinhibition mechanism of proto-Dbl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Regulatory and signaling properties of the Vav family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Does Vav bind to F‐actin through a CH domain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

The Dbl family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Genomic analysis of metastasis reveals an essential role for RhoC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Biological assays for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Lck regulates Vav activation of members of the Rho family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Asef, a link between the tumor suppressor APC and G-protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Oncogene ect2 is related to regulators of small GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Vav family proteins couple to diverse cell surface receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Rho GTPases and signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

APS, an adaptor protein containing Pleckstrin homology (PH) and Src homology-2 (SH2) domains inhibits the JAK-STAT pathway in collaboration with c-Cbl

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

Single calponin homology domains are not actin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

7 January 2021

The yeast tribrid system--genetic detection of trans-phosphorylated ITAM-SH2-interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

7 January 2021

Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205927

1 reference

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205927

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Dimensions Publication ID

31 July 2017

1006662343

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1 reference