(Q24515205)

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Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 July 2017

Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

cell morphology

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inferred from title

Michael McClelland

object named as

M McClelland

6

author given names

M

author last names

McClelland

1 reference

PubMed publication ID

20 October 2023

author name string

L Zeng

1

author given names

L

author last names

Zeng

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

P Sachdev

2

author given names

P

author last names

Sachdev

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

L Yan

3

author given names

L

author last names

Yan

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

J L Chan

4

author given names

J L

author last names

Chan

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

T Trenkle

5

author given names

T

author last names

Trenkle

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

J Welsh

7

author given names

J

author last names

Welsh

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

L H Wang

8

author given names

L H

author last names

Wang

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

language of work or name

0 references

publication date

1 December 2000

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

Molecular and Cellular Biology

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Europe PubMed Central

PubMed publication ID

1 July 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

9212-9224

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

Regulatory and signaling properties of the Vav family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Binding of Vav to Grb2 through dimerization of Src homology 3 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Transformation of intact yeast cells treated with alkali cations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Rho GTPases and the actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Nuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic differentiation of HL-60 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Structure and function of vav

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Vav is associated with signal transducing molecules gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin-6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Association of a p95 Vav-containing signaling complex with the FcepsilonRI gamma chain in the RBL-2H3 mast cell line. Evidence for a constitutive in vivo association of Vav with Grb2, Raf-1, and ERK2 in an active complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Vav2 is an activator of Cdc42, Rac1, and RhoA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Rho GTPases and signaling networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Tyrosine phosphorylation of the vav proto-oncogene product links FcepsilonRI to the Rac1-JNK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

Lck regulates Vav activation of members of the Rho family of GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

The proline-rich region of Vav binds to Grb2 and Grb3-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

19 March 2017

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

7 April 2017

Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Mechanism of activation of Pak1 kinase by membrane localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Signaling through CD5 activates a pathway involving phosphatidylinositol 3-kinase, Vav, and Rac1 in human mature T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

The VAV family of signal transduction molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Insulin-like growth factor-1 induces rapid tyrosine phosphorylation of the vav proto-oncogene product.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Vav binds to several SH2/SH3 containing proteins in activated lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Hematopoietic development of vav-/- mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

A functional T-cell receptor signaling pathway is required for p95vav activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Signal transduction in T lymphocytes using a conditional allele of Sos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Insulin-dependent tyrosine phosphorylation of the vav protooncogene product in cells of hematopoietic origin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Mechanism of activation of the vav protooncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

The proto-oncogene c-ros codes for a transmembrane tyrosine protein kinase sharing sequence and structural homology with sevenless protein of Drosophila melanogaster.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

Interferon alpha induces rapid tyrosine phosphorylation of the vav proto-oncogene product in hematopoietic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

27 September 2017

The CDC42-specific inhibitor derived from ACK-1 blocks v-Ha-Ras-induced transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

30 May 2018

N-terminally truncated Vav induces the formation of depolymerization-resistant actin filaments in NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

30 May 2018

Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

30 May 2018

Tissue and epithelial cell-specific expression of chicken proto-oncogene c-ros in several organs suggests that it may play roles in their development and mature functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

30 May 2018

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

30 May 2018

CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102179

29 November 2018

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of serum response factor by RhoA is mediated by the nuclear factor-kappaB and C/EBP transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of a p95 Vav-containing Signaling Complex with the FcϵRI γ Chain in the RBL-2H3 Mast Cell Line

1 reference

https://api.crossref.org/works/10.1128%2FMCB.20.24.9212-9224.2000

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1128/MCB.20.24.9212-9224.2000

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

release_bc33lqeycrdvhdn4u2a5mnqx6a

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1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 July 2017

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