(Q34157752)

31 July 2017

1 reference

title

The biological and metabolic fates of endogenous DNA damage products (English)

1 reference

31 July 2017

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Peter C Dedon

2

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author name string

Simon Wan Chan

series ordinal

1

1 reference

31 July 2017

16 December 2010

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31 July 2017

Journal of Nucleic Acids

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31 July 2017

2010

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31 July 2017

929047

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Creative Commons Attribution 3.0 Unported

31 July 2017

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry

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DNA repair of oxidative DNA damage in human carcinogenesis: potential application for cancer risk assessment and prevention

5 July 2018

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Measurement and meaning of oxidatively modified DNA lesions in urine

5 July 2018

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Bulky DNA lesions induced by reactive oxygen species

5 July 2018

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Biological properties of single chemical-DNA adducts: a twenty year perspective

5 July 2018

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The chemical toxicology of 2-deoxyribose oxidation in DNA.

5 July 2018

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Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: a review of published adduct types and levels in humans

5 July 2018

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Base-excision repair of oxidative DNA damage

5 July 2018

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DNA adduct profiles: chemical approaches to addressing the biological impact of DNA damage from small molecules

5 July 2018

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Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation

5 July 2018

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N-formylation of lysine in histone proteins as a secondary modification arising from oxidative DNA damage

5 July 2018

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Aerobic fate of the C-3'-thymidinyl radical in single-stranded DNA.

5 July 2018

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Formation of 1,4-dioxo-2-butene-derived adducts of 2'-deoxyadenosine and 2'-deoxycytidine in oxidized DNA.

5 July 2018

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In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG.

5 July 2018

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Mutagenesis at methylated CpG sequences.

5 July 2018

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Detection of DNA adducts derived from the reactive metabolite of furan, cis-2-butene-1,4-dial

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Endogenous lipid hydroperoxide-mediated DNA-adduct formation in min mice.

5 July 2018

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Mass spectroscopic characterization of protein modification by malondialdehyde

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxide

5 July 2018

1 reference

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The Nudix hydrolase superfamily

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Cyclooxygenase-2-mediated DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Novel lipid hydroperoxide-derived hemoglobin histidine adducts as biomarkers of oxidative stress.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Oxidative DNA damage and disease: induction, repair and significance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Endogenous DNA damage in humans: a review of quantitative data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Reactive nitrogen species in the chemical biology of inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Half-life and DNA strand scission products of 2-deoxyribonolactone oxidative DNA damage lesions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Measurement of the malondialdehyde-2'-deoxyguanosine adduct in human urine by immuno-extraction and liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Enzymology of repair of etheno-adducts.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Intracellular metabolism of 4-hydroxynonenal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Oxy radicals, lipid peroxidation and DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Lipid peroxidation in aging brain and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Role of endogenous oxidative DNA damage in carcinogenesis: what can we learn from repair-deficient mice?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Reactivity and mutagenicity of endogenous DNA oxopropenylating agents: base propenals, malondialdehyde, and N(epsilon)-oxopropenyllysine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

The importance of lipid-derived malondialdehyde in diabetes mellitus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Oxyradicals and DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Lipid peroxidation-DNA damage by malondialdehyde

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Etheno DNA-base adducts from endogenous reactive species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Properties and biological functions of the NTH and FPG proteins of Escherichia coli: two DNA glycosylases that repair oxidative damage in DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Metabolic studies of allopurinol, an inhibitor of xanthine oxidase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

A highly basic histone H4 domain bound to the sharply bent region of nucleosomal DNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Identification of adducts formed by reaction of guanine nucleosides with malondialdehyde and structurally related aldehydes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

Change in the pattern of histone binding to DNA upon transcriptional activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

High urinary excretion of lipid peroxidation-derived DNA damage in patients with cancer-prone liver diseases

5 July 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Lipid peroxidation and etheno DNA adducts in white blood cells of liver fluke-infected patients: protection by plasma alpha-tocopherol and praziquantel

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

High excretion of etheno adducts in liver fluke-infected patients: protection by praziquantel against DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Increased urinary 1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytidine excretion in thalassemia patients: markers for lipid peroxidation-induced DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Effect of gender and cigarette smoking on urinary excretion of etheno DNA adducts in humans measured by isotope dilution gas chromatography/mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Metabolism in vitro and in vivo of the DNA base adduct, M1G.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Peroxynitrite reacts with 8-nitropurines to yield 8-oxopurines

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Absence of 2'-deoxyoxanosine and presence of abasic sites in DNA exposed to nitric oxide at controlled physiological concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

4-Hydroperoxy-2-nonenal-induced formation of 1,N2-etheno-2'-deoxyguanosine adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Simultaneous quantification of three lipid peroxidation-derived etheno adducts in human DNA by stable isotope dilution nanoflow liquid chromatography nanospray ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Characterization of an N6-oxopropenyl-2'-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospray ionization tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Analysis of M1G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Comparison of DNA adduct levels associated with oxidative stress in human pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Formation of the 1,N2-glyoxal adduct of deoxyguanosine by phosphoglycolaldehyde, a product of 3'-deoxyribose oxidation in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Independent generation and characterization of a C2'-oxidized abasic site in chemically synthesized oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Reaction of 2'-deoxyribonucleosides with cis- and trans-1,4-dioxo-2-butene

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

5'-(2-phosphoryl-1,4-dioxobutane) as a product of 5'-oxidation of deoxyribose in DNA: elimination as trans-1,4-dioxo-2-butene and approaches to analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Characterization of nucleoside adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme endonuclease III.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Structural basis of protein-bound endogenous aldehydes. Chemical and immunochemical characterizations of configurational isomers of a 4-hydroxy-2-nonenal-histidine adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Modification of heat shock protein 90 by 4-hydroxynonenal in a rat model of chronic alcoholic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Protein-bound 4-hydroxy-2-hexenal as a marker of oxidized n-3 polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Model Studies on Protein Side Chain Modification by 4-Oxo-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Identification of a new cross-link and unique histidine adduct from bovine serum albumin incubated with malondialdehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

A reactive metabolite of furan, cis-2-butene-1,4-dial, is mutagenic in the Ames assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010698

One-electron oxidation of DNA and inflammation processes

28 October 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

Characterization of Amino Acid and Glutathione Adducts ofcis-2-Butene-1,4-dial, a Reactive Metabolite of Furan

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F929047

An improved 32P-postlabeling/high-performance liquid chromatography method for the analysis of the malondialdehye-derived 1, N2-propanodeoxyguanosine DNA adduct in animal and human tissues

21 January 2018

1 reference

12 December 2020

Effect of dietary virgin olive oil on urinary excretion of etheno–DNA adducts

1 reference

12 December 2020

Human liver oxidative metabolism of O6-benzylguanine

1 reference

12 December 2020

Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver

1 reference

12 December 2020

Increased levels of promutagenic etheno-DNA adducts in colonic polyps of FAP patients

1 reference

12 December 2020

Determination of malondialdehyde-induced DNA damage in human tissues using an immunoslot blot assay

1 reference

12 December 2020

Analysis of the malondialdehyde-2'-deoxyguanosine adduct pyrimidopurinone in human leukocyte DNA by gas chromatography/electron capture/negative chemical ionization/mass spectrometry

1 reference

12 December 2020

Identifiers

DOI

10.4061/2010/929047

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

21209721