(Q34162245)

31 July 2017

title

A novel chromosomal inversion at 11q23 in infant acute myeloid leukemia fuses MLL to CALM, a gene that encodes a clathrin assembly protein (English)

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31 July 2017

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acute myeloid leukemia

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Daniel S Wechsler

1

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31 July 2017

Lars D Engstrom

2

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31 July 2017

Brian M Alexander

3

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31 July 2017

David G Motto

4

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31 July 2017

Diane Roulston

5

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31 July 2017

publication date

1 January 2003

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Genes, Chromosomes and Cancer

31 July 2017

published in

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31 July 2017

volume

36

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31 July 2017

issue

1

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31 July 2017

page(s)

26-36

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Cell-free expression and functional reconstitution of CALM in clathrin assembly

31 July 2017

cites work

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The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.

21 January 2018

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Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic

21 January 2018

1 reference

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

21 January 2018

1 reference

7 January 2021

Molecular analysis of the CALM/AF10 fusion: identical rearrangements in acute myeloid leukemia, acute lymphoblastic leukemia and malignant lymphoma patients

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7 January 2021

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

1 reference

7 January 2021

Identification and molecular characterization of CALM/AF10fusion products in T cell acute lymphoblastic leukemia and acute myeloid leukemia

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7 January 2021

The amino terminus of the mixed lineage leukemia protein (MLL) promotes cell cycle arrest and monocytic differentiation

1 reference

7 January 2021

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

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7 January 2021

Endocytosis and mitogenic signaling

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7 January 2021

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

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7 January 2021

The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family

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7 January 2021

MLL genomic breakpoint distribution within the breakpoint cluster region in de novo leukemia in children

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7 January 2021

Endocytosis proteins and cancer: a potential link?

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7 January 2021

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

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7 January 2021

Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots

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7 January 2021

Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis.

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7 January 2021

Identification and molecular characterisation of a CALM-AF10 fusion in acute megakaryoblastic leukaemia.

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7 January 2021

Properties of GST-CALM expressed in E. coli

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7 January 2021

Hematologic malignancies with the t(10;11) (p13;q21) have the same molecular event and a variety of morphologic or immunologic phenotypes

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7 January 2021

Mixed-lineage leukemia with t(10;11)(p13;q21): an analysis of AF10-CALM and CALM-AF10 fusion mRNAs and clinical features

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7 January 2021

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

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7 January 2021

The t(10;11)(p12;q23) translocation in acute leukaemia: a cytogenetic and clinical study of 20 patients. European 11q23 Workshop participants

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7 January 2021

ATM binds to beta-adaptin in cytoplasmic vesicles

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7 January 2021

Enhanced direct amplification of Guthrie card DNA following selective elution of PCR inhibitors

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7 January 2021

Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

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7 January 2021

Panhandle PCR for cDNA: a rapid method for isolation of MLL fusion transcripts involving unknown partner genes

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7 January 2021

Consistent detection of CALM-AF10 chimaeric transcripts in haematological malignancies with t(10;11)(p13;q14) and identification of novel transcripts

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7 January 2021

Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene

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7 January 2021

Maternal diet and infant leukemia: A role for DNA topoisomerase II inhibitors?

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7 January 2021

Dietary flavonoids and the MLL gene: A pathway to infant leukemia?

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7 January 2021

Backtracking leukemia to birth

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7 January 2021

CALM-AF10 fusion gene in leukemias: simple and inversion-associated translocation (10;11).

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7 January 2021

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7 January 2021

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

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7 January 2021

Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14-q21) suggests a potential role for truncated AF10 polypeptides

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7 January 2021

EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia

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7 January 2021

The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis

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7 January 2021

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

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7 January 2021

Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations

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7 January 2021

Nucleocytoplasmic shuttling of endocytic proteins

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7 January 2021

Control of EGF receptor signaling by clathrin-mediated endocytosis.

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7 January 2021

Identifiers

DOI

10.1002/GCC.10136

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31 July 2017

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