(Q34163219)

31 July 2017

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title

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition (English)

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31 July 2017

Andrew Tutt

1

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31 July 2017

Alan Ashworth

series ordinal

2

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31 July 2017

language of work or name

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1 December 2002

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Trends in Molecular Medicine

31 July 2017

published in

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31 July 2017

volume

8

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31 July 2017

issue

12

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31 July 2017

page(s)

571-576

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THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

31 July 2017

cites work

1 reference

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Cancer susceptibility and the functions of BRCA1 and BRCA2

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Defying death after DNA damage.

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The DNA damage response: putting checkpoints in perspective

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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

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hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

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7 January 2021

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

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Association of BRCA1 with Rad51 in mitotic and meiotic cells

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Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

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7 January 2021

Brca1 controls homology-directed DNA repair

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DNA double strand break repair in mammalian cells

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7 January 2021

Nucleotide excision repair in mammalian cells

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Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

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BRCA1 required for transcription-coupled repair of oxidative DNA damage

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BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair.

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7 January 2021

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

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Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

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Genomic instability in mice lacking histone H2AX

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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

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7 January 2021

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

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7 January 2021

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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7 January 2021

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

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7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

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7 January 2021

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

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7 January 2021

Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

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7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

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7 January 2021

BRCA2 is required for homology-directed repair of chromosomal breaks

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7 January 2021

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

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7 January 2021

Involvement of Brca2 in DNA repair

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7 January 2021

Disruption of Brca2 increases the spontaneous mutation rate in vivo: synergism with ionizing radiation

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7 January 2021

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

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7 January 2021

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

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7 January 2021

Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations

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7 January 2021

Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals

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7 January 2021

Cancer. BRCA2 enters the fray

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7 January 2021

Biallelic inactivation of BRCA2 in Fanconi anemia

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Biomedicine. D-Day for BRCA2

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7 January 2021

Breast cancer and Fanconi anemia: what are the connections?

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7 January 2021

The emerging genetic and molecular basis of Fanconi anaemia

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7 January 2021

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

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7 January 2021

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

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7 January 2021

Dominant Negative ATM Mutations in Breast Cancer Families

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7 January 2021

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

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7 January 2021

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Identifiers

DOI

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31 July 2017

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