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Molecular determinants of TCR expression and selection.
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Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Molecular determinants of TCR expression and selection
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author
Joonsoo Kang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author name string
L J Berg
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
publication date
1 April 2001
1 reference
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Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
13
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
232-241
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility
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Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes
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The interleukin 7 receptor is required for T cell receptor gamma locus accessibility to the V(D)J recombinase
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PIM1 reconstitutes thymus cellularity in interleukin 7- and common gamma chain-mutant mice and permits thymocyte maturation in Rag- but not CD3gamma-deficient mice
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7 January 2021
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Interleukin 7 receptor-deficient mice lack gammadelta T cells
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7 January 2021
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Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor
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Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements
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V(D)J recombination is not activated by demethylation of the kappa locus
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A role for histone acetylation in the developmental regulation of VDJ recombination.
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Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination
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Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling
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7 January 2021
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Induction of germline transcription in the TCRgamma locus by Stat5: implications for accessibility control by the IL-7 receptor
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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
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Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms
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SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression
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E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
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7 January 2021
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Positive and negative regulation of V(D)J recombination by the E2A proteins
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7 January 2021
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E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells
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7 January 2021
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Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB
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Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice
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7 January 2021
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Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective requirement for MAP kinase activation in thymocyte differentiation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive and negative selection invoke distinct signaling pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tec family kinases modulate thresholds for thymocyte development and selection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD3delta couples T-cell receptor signalling to ERK activation and thymocyte positive selection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEK activity regulates negative selection of immature CD4+CD8+ thymocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degree of ERK activation influences both positive and negative thymocyte selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
JNK is required for effector T-cell function but not for T-cell activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
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Antigen-specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lck activity controls CD4/CD8 T cell lineage commitment.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Csk controls antigen receptor-mediated development and selection of T-lineage cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of T cell fate by Notch
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch signaling in T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Notch and the immune system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 coreceptor extinction in signaled CD4(+)CD8(+) thymocytes: coordinate roles for both transcriptional and posttranscriptional regulatory mechanisms in developing thymocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
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The influence of the MAPK pathway on T cell lineage commitment
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for RORgamma in thymocyte survival and lymphoid organ development
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New member of the winged-helix protein family disrupted in mouse and rat nude mutations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two genetically separable steps in the differentiation of thymic epithelium.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hoxa3 and pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
GKLF in thymus epithelium as a developmentally regulated element of thymocyte-stroma cross-talk
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for pref-1 and HES-1 in thymocyte development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro models of T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for thymic mesenchyme in early T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoids in T cell development and function*.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2800%2900209-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(00)00209-0
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed publication ID
11228418
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11228418
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11228418%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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