(Q34171445)

English

Blockade of dopamine D₃ but not D₂ receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Blockade of dopamine D₃ but not D₂ receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

0 references

0 references

social isolation

1 reference

based on heuristic

inferred from title

author name string

David J G Watson

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Charles A Marsden

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Mark J Millan

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Kevin C F Fone

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

publication date

18 March 2011

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

The International Journal of Neuropsychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

471-484

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Selective blockade of dopamine D(3) versus D(2) receptors enhances frontocortical cholinergic transmission and social memory in rats: a parallel neurochemical and behavioural analysis.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Cognitive impairment in schizophrenia: a review of developmental and genetic models, and pro-cognitive profile of the optimised D(3) > D(2) antagonist, S33138.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Enhanced cognitive performance of dopamine D3 receptor "knock-out" mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Blockade of dopamine D(3) receptors in frontal cortex, but not in sub-cortical structures, enhances social recognition in rats: similar actions of D(1) receptor agonists, but not of D(2) antagonists

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Isolation rearing and hyperlocomotion are associated with reduced immediate early gene expression levels in the medial prefrontal cortex.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Metabotropic glutamate mGlu1 receptor stimulation and blockade: therapeutic opportunities in psychiatric illness

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Influence of postweaning social isolation in the rat on brain development, conditioned behavior, and neurotransmission

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Effects of noradrenaline depletion in the brain on response on novelty in isolation-reared rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Selective dopamine D3 receptor antagonists enhance cortical acetylcholine levels measured with high-performance liquid chromatography/tandem mass spectrometry without anti-cholinesterases.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Social isolation selectively reduces hippocampal brain-derived neurotrophic factor without altering plasma corticosterone

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Formulation and evaluation of metronidazole acid gel for vaginal contraception

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Increased dopamine D2High receptors in rats reared in social isolation

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Impact of regional 5-HT depletion on the cognitive enhancing effects of a typical 5-ht(6) receptor antagonist, Ro 04-6790, in the Novel Object Discrimination task

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Dopamine D3 receptor agonists for protection and repair in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Dopamine D3 receptor antagonists as therapeutic agents

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

The mGluR2/3 agonist LY379268 reverses post-weaning social isolation-induced recognition memory deficits in the rat.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

A peripheral marker for schizophrenia: Increased levels of D3 dopamine receptor mRNA in blood lymphocytes

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Autoradiographic distribution of D3-type dopamine receptors in human brain using [3H]7-hydroxy-N,N-di-n-propyl-2-aminotetralin

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Current perspectives on selective dopamine D(3) receptor antagonists as pharmacotherapeutics for addictions and related disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Mesolimbic dopamine D3 receptors and use of antipsychotics in patients with schizophrenia. A postmortem study.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Reversal of a cholinergic-induced deficit in a rodent model of recognition memory by the selective 5-HT6 receptor antagonist, Ro 04-6790.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

5-ht6 receptors

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

D3 dopamine receptor mRNA is widely expressed in the human brain

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Effects of hippocampal lesions on patterned motor learning in the rat.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Mice lacking dopamine D2 and D3 receptors exhibit differential activation of prefrontal cortical neurons during tasks requiring attention

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Behavioural comparisons between individually- and group-housed male rats: effects of novel environments and diurnal rhythm.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Retrograde and anterograde object recognition in rats with hippocampal lesions.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Dopaminergic modulation of risk-based decision making

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

The dopamine D3/D2 receptor agonist 7-OH-DPAT induces cognitive impairment in the marmoset.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Increased 5-HT2C receptor responsiveness occurs on rearing rats in social isolation.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Selective blockade of D(3) dopamine receptors enhances the anti-parkinsonian properties of ropinirole and levodopa in the MPTP-lesioned primate.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Opposite effects of dopamine D2 and D3 receptors on learning and memory in the rat.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Spontaneous object recognition and object location memory in rats: the effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Cortico-Basal Ganglia reward network: microcircuitry

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Psychosis pathways converge via D2high dopamine receptors

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Effects of social isolation rearing on the limbic brain: a combined behavioral and magnetic resonance imaging volumetry study in rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Intra-accumbens infusion of D(3) receptor agonists reduces spontaneous and dopamine-induced locomotion.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiologic

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

The role of dopamine D3 compared with D2 receptors in the control of locomotor activity: a combined behavioural and neurochemical analysis with novel, selective antagonists in rats

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: I. Receptor-binding profile and functio

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Hyperactivity to novelty induced by social isolation is not correlated with changes in D2 receptor function and binding in striatum

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

D3 dopamine receptor, behavioral sensitization, and psychosis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Multiple variants of the DRD3, but not BDNF gene, influence age-at-onset of schizophrenia.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Reversal of isolation-rearing-induced PPI deficits by an alpha7 nicotinic receptor agonist

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Relative expression of D3 dopamine receptor and alternative splice variant D3nf mRNA in high and low responders to novelty

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

What does the anatomical organization of the entorhinal cortex tell us?

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Dopamine D2 receptor knock-out mice are insensitive to the hypolocomotor and hypothermic effects of dopamine D2/D3 receptor agonists

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Fluoxetine administration modulates the cytoskeletal microtubular system in the rat hippocampus.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Chronic fluoxetine differentially modulates the hippocampal microtubular and serotonergic system in grouped and isolation reared rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Behavioral indices in antipsychotic drug discovery

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Isolation rearing induces recognition memory deficits accompanied by cytoskeletal alterations in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Reversal of isolation rearing-induced deficits in prepulse inhibition by Seroquel and olanzapine

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

H3 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing retrieval

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

The effects of isolation rearing on exploration in the rat

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

21 January 2018

Selective antagonism at dopamine D3 receptors enhances monoaminergic and cholinergic neurotransmission in the rat anterior cingulate cortex

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective expression of dopamine D3 receptor mRNA in proliferative zones during embryonic development of the rat brain.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Dopamine D3 receptors expressed by all mesencephalic dopamine neurons

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Possible implications of the dopamine D(3) receptor in schizophrenia and in antipsychotic drug actions

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenyl-acetamide), a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: III. Actions in models of therapeutic

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other "D-2-like" agonists

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Heterogeneity of behavioural profile between three new putative selective D3 dopamine receptor antagonists using an ethologically based approach

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligonucleotide-induced reduction in 5-hydroxytryptamine7 receptors in the rat hypothalamus without alteration in exploratory behaviour or neuroendocrine function

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

The dopamine D3 receptor antagonist NGB 2904 increases spontaneous and amphetamine-stimulated locomotion

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000435

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1017/S1461145711000435

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34171445&oldid=1976613708"