(Q34171831)

31 July 2017

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title

Future of GPR109A agonists in the treatment of dyslipidaemia (English)

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31 July 2017

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D Wanders

1

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31 July 2017

R L Judd

series ordinal

2

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31 July 2017

publication date

1 August 2011

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Diabetes, Obesity and Metabolism

31 July 2017

published in

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31 July 2017

volume

13

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31 July 2017

issue

8

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31 July 2017

page(s)

685-691

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Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

31 July 2017

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21 January 2018

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21 January 2018

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Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice

21 January 2018

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21 January 2018

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Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells

21 January 2018

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beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice

21 January 2018

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21 January 2018

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Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells

21 January 2018

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Effects of Nicotinic Acid Therapy on Plasma High Density Lipoprotein Subfraction Distribution and Composition and on Apolipoprotein A Metabolism

21 January 2018

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Niacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterol

21 January 2018

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Nicotinic acid: recent developments

21 January 2018

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Mechanism of action of niacin

21 January 2018

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Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin

21 January 2018

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Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways

21 January 2018

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Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice.

21 January 2018

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Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells

21 January 2018

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21 January 2018

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The nicotinic acid receptor GPR109A (HM74A or PUMA-G) as a new therapeutic target

21 January 2018

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Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review

21 January 2018

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Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans

21 January 2018

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21 January 2018

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A comparison of acipimox and nicotinic acid in type 2b hyperlipidaemia

21 January 2018

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Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects.

21 January 2018

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Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.

21 January 2018

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3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in mice.

21 January 2018

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Pyrazole derivatives as partial agonists for the nicotinic acid receptor

21 January 2018

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21 January 2018

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Anthranilic acid replacements in a niacin receptor agonist

21 January 2018

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Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: Optimization of in vitro activity

21 January 2018

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Characterization of determinants of ligand binding to the nicotinic acid receptor GPR109A (HM74A/PUMA-G).

21 January 2018

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Molecular modeling aided design of nicotinic acid receptor GPR109A agonists

21 January 2018

1 reference

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Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humans

21 January 2018

1 reference

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GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01400.X

Elucidation of signaling and functional activities of an orphan GPCR, GPR81.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01400.X

Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01400.X

Role of GPR81 in lactate-mediated reduction of adipose lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01400.X

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01400.X

An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01400.X

10.1111/J.1463-1326.2011.01400.X

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference