(Q34175818)

31 July 2017

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title

LNA: a versatile tool for therapeutics and genomics (English)

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31 July 2017

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Michael Petersen

1

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31 July 2017

Jesper Wengel

series ordinal

2

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31 July 2017

publication date

1 February 2003

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31 July 2017

published in

Trends in Biotechnology

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31 July 2017

volume

21

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31 July 2017

issue

2

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31 July 2017

page(s)

74-81

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Antisense oligonucleotides: a new therapeutic principle

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Conformationally restricted carbohydrate-modified nucleic acids and antisense technology

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

LNA (Locked Nucleic Acid): An RNA Mimic Forming Exceedingly Stable LNA:LNA Duplexes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Synthesis of 3‘-C- and 4‘-C-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: conformational tuning and high-affinity recognition of DNA/RNA targets.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Synthesis of 2′-O,4′-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C3, -endo sugar puckering

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Inhibition of HIV-1 Tat-dependent trans activation by steric block chimeric 2'-O-methyl/LNA oligoribonucleotides.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Locked nucleic acid (LNA): fine-tuning the recognition of DNA and RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Design of antisense oligonucleotides stabilized by locked nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Synthesis of Abasic Locked Nucleic Acid and Twoseco-LNA Derivatives and Evaluation of Their Hybridization Properties Compared with Their More Flexible DNA Counterparts

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

The first analogues of LNA (Locked Nucleic Acids): Phosphorothioate-LNA and 2′-thio-LNA

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Inhibition of ICAM-1 gene expression by antisense 2',4'-BNA oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Stopped-flow kinetics of locked nucleic acid (LNA)-oligonucleotide duplex formation: studies of LNA-DNA and DNA-DNA interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Protonated DNA structures

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Branched oligonucleotides containing bicyclic nucleotides as branching points and DNA or LNA as triplex forming branch

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

2'-O,4'-C-Methylene bridged nucleic acid (2',4'-BNA): synthesis and triplex-forming properties

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

2'-O,4'-C-methylene bridged nucleic acid modification promotes pyrimidine motif triplex DNA formation at physiological pH: thermodynamic and kinetic studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

A 2′,4′-Bridged Nucleic Acid Containing 2-Pyridone as a Nucleobase: Efficient Recognition of a C⋅G Interruption by Triplex Formation with a Pyrimidine Motif

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Solution Structure of an Intramolecular Pyrimidine−Purine−Pyrimidine Triplex Containing an RNA Third Strand

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Solution Structure of an LNA Hybridized to DNA: NMR Study of the d(CTLGCTLTLCTLGC):d(GCAGAAGCAG) Duplex Containing Four Locked Nucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

The conformations of locked nucleic acids (LNA)

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

New candidates for true antisense

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Molecular mechanisms of action of antisense drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Novel antisense and peptide nucleic acid strategies for controlling gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Selecting optimal antisense reagents

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Two problems in antisense biotechnology: in vitro delivery and the design of antisense experiments

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

alpha-L-ribo-configured locked nucleic acid (alpha-L-LNA): synthesis and properties

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

1 reference

7 January 2021

Pseudo--half-knot formation with RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

The RNA component of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

LNA-enhanced detection of single nucleotide polymorphisms in the apolipoprotein E.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Single nucleotide polymorphism genotyping using short, fluorescently labeled locked nucleic acid (LNA) probes and fluorescence polarization detection

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Regulation of gene expression with double-stranded phosphorothioate oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

Design and characterization of decoy oligonucleotides containing locked nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

RNA cleavage by the 10-23 DNA enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2900038-0

7 January 2021

10.1016/S0167-7799(02)00038-0

Identifiers

DOI

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31 July 2017

1 reference