(Q34179164)

31 July 2017

title

Structure-based design and screening of inhibitors for an essential bacterial GTPase, Der. (English)

1 reference

31 July 2017

2

Vladimir Tseitin

1 reference

31 July 2017

Jihwan Hwang

1

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31 July 2017

Kal Ramnarayan

series ordinal

3

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31 July 2017

Mark D Shenderovich

series ordinal

4

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31 July 2017

Masayori Inouye

series ordinal

5

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31 July 2017

publication date

29 February 2012

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The Journal of Antibiotics

31 July 2017

published in

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31 July 2017

volume

65

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31 July 2017

issue

5

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31 July 2017

page(s)

237-243

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Vancomycin resistance: occurrence, mechanisms and strategies to combat it.

31 July 2017

cites work

1 reference

Energy coupling in DNA gyrase and the mechanism of action of novobiocin

21 January 2018

1 reference

The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

1 reference

The GTPase superfamily: conserved structure and molecular mechanism

21 January 2018

1 reference

Function of the universally conserved bacterial GTPases

21 January 2018

1 reference

G protein mechanisms: insights from structural analysis

21 January 2018

1 reference

An essential GTPase, der, containing double GTP-binding domains from Escherichia coli and Thermotoga maritima

21 January 2018

1 reference

The tandem GTPase, Der, is essential for the biogenesis of 50S ribosomal subunits in Escherichia coli.

21 January 2018

1 reference

RelA functionally suppresses the growth defect caused by a mutation in the G domain of the essential Der protein

21 January 2018

1 reference

Interaction of an essential Escherichia coli GTPase, Der, with the 50S ribosome via the KH-like domain

21 January 2018

1 reference

A bacterial GAP-like protein, YihI, regulating the GTPase of Der, an essential GTP-binding protein in Escherichia coli.

21 January 2018

1 reference

Domain arrangement of Der, a switch protein containing two GTPase domains

21 January 2018

1 reference

The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding

21 January 2018

1 reference

Distinct GDP/GTP bound states of the tandem G-domains of EngA regulate ribosome binding.

21 January 2018

1 reference

Cooperative and critical roles for both G domains in the GTPase activity and cellular function of ribosome-associated Escherichia coli EngA.

21 January 2018

1 reference

Overexpression of two different GTPases rescues a null mutation in a heat-induced rRNA methyltransferase

21 January 2018

1 reference

Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant

21 January 2018

1 reference

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

21 January 2018

1 reference

Structure-based phenotyping predicts HIV-1 protease inhibitor resistance

21 January 2018

1 reference

Modeling, mutagenesis, and structural studies on the fully conserved phosphate-binding loop (loop 8) of triosephosphate isomerase: toward a new substrate specificity

21 January 2018

1 reference

The basis for resistance to beta-lactam antibiotics by penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

Penicillin-binding proteins and bacterial resistance to beta-lactams

21 January 2018

1 reference

Effects of the antibiotic pulvomycin on the elongation factor Tu-dependent reactions. Comparison with other antibiotics

21 January 2018

1 reference

The antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation.

21 January 2018

1 reference

The translation initiation functions of IF2: targets for thiostrepton inhibition.

21 January 2018

1 reference

Berberine targets assembly of Escherichia coli cell division protein FtsZ.

21 January 2018

1 reference

N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli

21 January 2018

1 reference

Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay

21 January 2018

1 reference

Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality

21 January 2018

1 reference

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

21 January 2018

1 reference

The specific inhibition of the DNA-directed RNA synthesis by rifamycin

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Enacyloxin IIa, an inhibitor of protein biosynthesis that acts on elongation factor Tu and the ribosome.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/JA.2012.9

1 reference

Dimensions Publication ID

31 July 2017

1034788692

0 references

1 reference