(Q34180577)

31 July 2017

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title

Biologically active dihydropyrimidones of the Biginelli-type--a literature survey (English)

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31 July 2017

C O Kappe

1

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31 July 2017

publication date

1 December 2000

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European Journal of Medicinal Chemistry

31 July 2017

published in

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31 July 2017

volume

35

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31 July 2017

issue

12

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31 July 2017

page(s)

1043-1052

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100 years of the biginelli dihydropyrimidine synthesis

31 July 2017

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Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines

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Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents

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Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents

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In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia

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Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.

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Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

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7 January 2021

Novel Alkaloids from the Sponge Batzella sp.: Inhibitors of HIV gp120-Human CD4 Binding

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7 January 2021

Calcium entry blockers and activators: conformational and structural determinants of dihydropyrimidine calcium channel modulators

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1,4-Dihydropyridines: Effects of Chirality and Conformation on the Calcium Antagonist and Calcium Agonist Activities

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1,4-Dihydropyridines--a basis for developing new drugs

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Dihydropyrimidines: novel calcium antagonists with potent and long-lasting vasodilative and antihypertensive activity.

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7 January 2021

Imidazo[1,5-a]pyrimidine and benzo[4,5]imidazo[1,2-a]pyrimidine derivatives as calcium antagonists

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7 January 2021

Ca2+ channel ligands: structure-function relationships of the 1,4-dihydropyridines

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7 January 2021

Molecular level model for the agonist/antagonist selectivity of the 1,4-dihydropyridine calcium channel receptor

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7 January 2021

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Synthesis and calcium antagonistic activity of some new 2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives

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7 January 2021

The development of human benign prostatic hyperplasia with age

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The Hytrin Community Assessment Trial study: a one-year study of terazosin versus placebo in the treatment of men with symptomatic benign prostatic hyperplasia. HYCAT Investigator Group.

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Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine

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7 January 2021

Design and synthesis of novel alpha1a adrenoceptor-selective dihydropyridine antagonists for the treatment of benign prostatic hyperplasia

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7 January 2021

Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinones

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Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification of linker and 4-methoxycarbonyl-4-phenylpiperidine moiety

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7 January 2021

Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 3. Approaches to eliminate opioid agonist metabolites by using substituted phenylpiperazine side chains

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7 January 2021

Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 4. Structure-activity relationship in the dihydropyrimidine series

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7 January 2021

Synthesis and evaluation of furo[3,4-d]pyrimidinones as selective alpha1a-adrenergic receptor antagonists.

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7 January 2021

Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle

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7 January 2021

Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis

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7 January 2021

Two New Synthetic Substances Active against Viruses of the Psittacosis-Lymphogranuloma-Trachoma Group

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7 January 2021

Experimental chemotherapy of infection with agents of the psittacosis-lymphogranuloma-trachoma group

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7 January 2021

Synthesis of some thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones as potential platelet aggregation inhibitors

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7 January 2021

Condensed heterocyclic compounds: synthesis and antiinflammatory activity of novel thiazolo[3,2-alpha] pyrimidines

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7 January 2021

Synthesis and anti-inflammatory activities of some thiazolo[3,2-a]pyrimidine derivatives

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7 January 2021

Synthesis and pharmacological study of new 3,4-dihydro-2H,6H-pyrimido-[2,1-b][1,3]thiazines

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7 January 2021

Structure-activity relationships of substituted 5H-thiazolo[3,2-a]pyrimidines as group 2 metabotropic glutamate receptor antagonists

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7 January 2021

10.1016/S0223-5234(00)01189-2

Identifiers

DOI

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31 July 2017

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