(Q34182861)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

review article

1 reference

title

Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: an orally active anti-cancer drug waiting for its call-of-duty? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Michael J. Kelso

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Hayden Matthews

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

English

0 references

publication date

1 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Cancer

30 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

2051-2061

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21544803%20AND%20SRC:MED&resulttype=core&format=json

Inhibition by amiloride of experimental carcinogenesis induced by azaserine in rat pancreas.

30 January 2020

cites work

1 reference

Inhibition by amiloride of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats

21 January 2018

1 reference

Chemoprevention by amiloride of experimental carcinogenesis in rat colon induced by azoxymethane.

21 January 2018

1 reference

Control of pulmonary metastases of rat mammary cancer by inhibition of uPA and COX-2, singly and in combination

21 January 2018

1 reference

Time and dose dependency of the suppression of pulmonary metastases of rat mammary cancer by amiloride

21 January 2018

1 reference

Structural and functional analysis of the Na+/H+ exchanger

21 January 2018

1 reference

NHE1, NHE2, and NHE4 contribute to regulation of cell pH in T84 colon cancer cells

21 January 2018

1 reference

The chronic administration of drugs that inhibit the regulation of intracellular pH: in vitro and anti-tumour effects

21 January 2018

1 reference

Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and motility

21 January 2018

1 reference

CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

21 January 2018

1 reference

Na+/H+ exchangers and RhoA regulate acidic extracellular pH-induced lysosome trafficking in prostate cancer cells

21 January 2018

1 reference

Reduction of intracellular pH inhibits the expression of VEGF in K562 cells after targeted inhibition of the Na+/H+ exchanger.

21 January 2018

1 reference

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

21 January 2018

1 reference

Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy

21 January 2018

1 reference

Glutamate 346 of human Na+-H+ exchanger NHE1 is crucial for modulating both the affinity for Na+ and the interaction with amiloride derivatives

21 January 2018

1 reference

Ethyl isopropyl amiloride inhibits smooth muscle cell proliferation and migration by inducing apoptosis and antagonizing urokinase plasminogen activator activity

21 January 2018

1 reference

Amiloride and its analogs as tools in the study of ion transport

21 January 2018

1 reference

Na+ :H+ exchange inhibition induces intracellular acidosis and differentially impairs cell growth and viability of human and rat hepatocarcinoma cells

21 January 2018

1 reference

Control of hepatocyte DNA synthesis by intracellular pH and its role in the action of tumor promoters

21 January 2018

1 reference

Modification of intracellular pH and thermotolerance development by amiloride

21 January 2018

1 reference

The relationship between thermosensitivity and intracellular pH in cells deficient in Na+/H+ antiport function

21 January 2018

1 reference

Sensitization to hyperthermia by intracellular acidification of C6 glioma cells.

21 January 2018

1 reference

Identification of acid-sensing ion channels in adenoid cystic carcinomas

21 January 2018

1 reference

Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration.

21 January 2018

1 reference

Altered proton extrusion in cells adapted to growth at low extracellular pH.

21 January 2018

1 reference

Amiloride-sensitive Na+ channels contribute to regulatory volume increases in human glioma cells

21 January 2018

1 reference

Acid-sensing ion channels in malignant gliomas

21 January 2018

1 reference

Amiloride potentiates TRAIL-induced tumor cell apoptosis by intracellular acidification-dependent Akt inactivation.

21 January 2018

1 reference

Role of HER-2/neu signaling in sensitivity to tumor necrosis factor-related apoptosis-inducing ligand: enhancement of TRAIL-mediated apoptosis by amiloride

21 January 2018

1 reference

Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer

21 January 2018

1 reference

The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

21 January 2018

1 reference

Association of plasminogen with dipeptidyl peptidase IV and Na+/H+ exchanger isoform NHE3 regulates invasion of human 1-LN prostate tumor cells

21 January 2018

1 reference

Structure-function relationships in the interaction between the urokinase-type plasminogen activator and its receptor

21 January 2018

1 reference

Revisiting the biological roles of PAI2 (SERPINB2) in cancer

21 January 2018

1 reference

The urokinase receptor: focused cell surface proteolysis, cell adhesion and signaling

21 January 2018

1 reference

Peptides and small molecules targeting the plasminogen activation system: towards prophylactic anti-metastasis drugs for breast cancer

21 January 2018

1 reference

Inhibitors of the proteolytic activity of urokinase type plasminogen activator

21 January 2018

1 reference

Amiloride selectively inhibits the urokinase-type plasminogen activator

21 January 2018

1 reference

Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design

21 January 2018

1 reference

Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion

21 January 2018

1 reference

Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger

21 January 2018

1 reference

Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin

21 January 2018

1 reference

Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives

21 January 2018

1 reference

Relation between drug treatment and cancer in hypertensives in the Swedish Trial in Old Patients with Hypertension 2: a 5-year, prospective, randomised, controlled trial

21 January 2018

1 reference

Selective optimization of side activities: another way for drug discovery

21 January 2018

1 reference

An overview of inhibitors of Na(+)/H(+) exchanger

21 January 2018

1 reference