(Q36263013)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Stephan J Reshkin

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Rosa A Cardone

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

1 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

786-795

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16175178%20AND%20SRC:MED&resulttype=core&format=json

MRI of the tumor microenvironment.

7 January 2020

cites work

1 reference

Breast cancer cells have a high capacity to acidify extracellular milieu by a dual mechanism

31 March 2020

1 reference

The relationship between extracellular lactate and tumour pH in a murine tumour model of ischaemia-reperfusion

31 March 2020

1 reference

Regulation of intracellular pH in eukaryotic cells

31 March 2020

1 reference

Microinjection of ras p21 induces a rapid rise in intracellular pH.

31 March 2020

1 reference

Activity and density of the Na+/H+ antiporter in normal and transformed human lymphocytes and fibroblasts

31 March 2020

1 reference

Intracellular pH is increased after transformation of Chinese hamster embryo fibroblasts

31 March 2020

1 reference

Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

31 March 2020

1 reference

Effect of Ha-ras on phosphatidylinositol metabolism, Na+/H+-antiporter and mobilization of intracellular calcium

31 March 2020

1 reference

Hydrogen ion-dependent oncogenesis and parallel new avenues to cancer prevention and treatment using a H(+)-mediated unifying approach: pH-related and pH-unrelated mechanisms

31 March 2020

1 reference

Role of intracellular pH in proliferation, transformation, and apoptosis

31 March 2020

1 reference

Lactate-proton cotransport in skeletal muscle

31 March 2020

1 reference

Expression profile of genes regulated by activity of the Na-H exchanger NHE1

31 March 2020

1 reference

Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species.

31 March 2020

1 reference

Induction of v-mos and activated Ha-ras oncogene expression in quiescent NIH 3T3 cells causes intracellular alkalinisation and cell-cycle progression

31 March 2020

1 reference

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

31 March 2020

1 reference

Why do cancers have high aerobic glycolysis?

31 March 2020

1 reference

Na(+)/H(+) exchange subtype 1 inhibition during extracellular acidification and hypoxia in glioma cells.

31 March 2020

1 reference

The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase

31 March 2020

1 reference

Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation

31 March 2020

1 reference

The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

31 March 2020

1 reference

Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines

31 March 2020

1 reference

CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

31 March 2020

1 reference

Dissemination and growth of cancer cells in metastatic sites

31 March 2020

1 reference

Tumor angiogenesis: past, present and the near future

31 March 2020

1 reference

Hydrogen ion dynamics and the Na+/H+ exchanger in cancer angiogenesis and antiangiogenesis.

31 March 2020

1 reference

31 March 2020

Mechanisms of metastasis

1 reference

Clinical, cellular, and molecular aspects of cancer invasion

31 March 2020

1 reference

Nm23-transfected MDA-mB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A31P nuclear magnetic resonance study in vivo and in vitro

31 March 2020

1 reference

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

31 March 2020

1 reference

Pericellular proteolysis by leukocytes and tumor cells on substrates: focal activation and the role of urokinase-type plasminogen activator

31 March 2020

1 reference

Release of the aspartyl protease cathepsin D is associated with and facilitates human breast cancer cell invasion

31 March 2020

1 reference

Unraveling the role of proteases in cancer

31 March 2020

1 reference

Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated protein kinase signaling.

31 March 2020

1 reference

Extracellular acidification alters lysosomal trafficking in human breast cancer cells

31 March 2020

1 reference

Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis

31 March 2020

1 reference

Involvement of phosphorylation of Tyr-31 and Tyr-118 of paxillin in MM1 cancer cell migration

31 March 2020

1 reference

Polarization of Na(+)/H(+) and Cl(-)/HCO (3)(-) exchangers in migrating renal epithelial cells

31 March 2020

1 reference

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

31 March 2020

1 reference

Prespecification and plasticity: shifting mechanisms of cell migration

31 March 2020

1 reference

Mechanisms of cancer cell invasion

31 March 2020

1 reference

Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion.

31 March 2020

1 reference

Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants.

31 March 2020

1 reference

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

31 March 2020

1 reference

Intravital imaging of cell movement in tumours

31 March 2020

1 reference

Autocrine activation of the hepatocyte growth factor receptor/met tyrosine kinase induces tumor cell motility by regulating pseudopodial protrusion

31 March 2020

1 reference

Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange

31 March 2020

1 reference

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

31 March 2020

1 reference

A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis

31 March 2020

1 reference

Foot and mouth: podosomes, invadopodia and circular dorsal ruffles

31 March 2020

1 reference

Calcitonin inhibits proton extrusion in resorbing rat osteoclasts via protein kinase A.

31 March 2020

1 reference

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

31 March 2020

1 reference

Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes

31 March 2020

1 reference

Diversity of the mammalian sodium/proton exchanger SLC9 gene family

31 March 2020

1 reference

Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac.

31 March 2020

1 reference

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

31 March 2020

1 reference

31 March 2020

1 reference

Cytosolic alkalinization increases stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism

31 March 2020

1 reference

p160ROCK mediates RhoA activation of Na-H exchange

31 March 2020

1 reference

Ezrin, a key component in tumor metastasis

31 March 2020

1 reference

Signaling through scaffold, anchoring, and adaptor proteins

31 March 2020

1 reference

Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy

31 March 2020

1 reference

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG).

31 March 2020

1 reference