(Q34187966)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Lin Jia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Yinyan Ma

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Shunxing Rong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jenna L Betters

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Ping Xie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Nanping Wang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Weiqing Tang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Liqing Yu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

publication date

10 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

3135-3144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Extracellular loop C of NPC1L1 is important for binding to ezetimibe

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

A novel membrane-based anti-diabetic action of atorvastatin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Selective versus total insulin resistance: a pathogenic paradox

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Sphingomyelinase activates GLUT4 translocation via a cholesterol-dependent mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Role of LXRs in control of lipogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Rat glucokinase gene: structure and regulation by insulin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

28 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Deficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Niemann-Pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Cellular mechanisms of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

A novel, noninvasive method for the measurement of intestinal fat absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Effects of a statin group drug, pravastatin, on the insulin resistance in patients with metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Effect of atorvastatin (10 mg/day) on glucose metabolism in patients with the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Dietary cholesterol reverses resistance to diet-induced weight gain in mice lacking Niemann-Pick C1-Like 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

LXRs regulate the balance between fat storage and oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M006353

Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

The epidemiology of nonalcoholic fatty liver disease in adults

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Molecular mediators of hepatic steatosis and liver injury

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952554

Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats

28 October 2018

1 reference

12 December 2020

Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance

1 reference

12 December 2020

Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice

1 reference

12 December 2020

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M006353

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699423%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference