(Q34189821)

31 July 2017

title

12/15-lipoxygenase is an interleukin-13 and interferon-γ counterregulated-mediator of allergic airway inflammation (English)

1 reference

31 July 2017

12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γCounterregulated-Mediator of Allergic Airway Inflammation (English)

1 reference

regulation of gene expression

4 August 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

4 August 2024

author name string

Margaret Crapster-Pregont

2

1 reference

31 July 2017

Yanjun Liu

3

1 reference

31 July 2017

Alexa R. Lindley

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

4 August 2024

Douglas A. Kuperman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

4 August 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20953328

4 August 2024

publication date

29 September 2010

1 reference

full work available at URL

31 July 2017

https://downloads.hindawi.com/journals/mi/2010/727305.pdf

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20953328/pdf/?tool=EBI

4 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20953328/?tool=EBI

4 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

https://europepmc.org/articles/PMC2952968

4 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

https://europepmc.org/articles/PMC2952968?pdf=render

4 August 2024

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20953328

http://downloads.hindawi.com/journals/mi/2010/727305.pdf

4 August 2024

1 reference

http://downloads.hindawi.com/journals/mi/2010/727305.xml

4 August 2024

1 reference

Mediators of Inflammation

4 August 2024

published in

1 reference

31 July 2017

volume

2010

1 reference

Creative Commons Attribution 3.0 Unported

31 July 2017

copyright license

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Immunobiology of asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Interleukin-4, interleukin-13, signal transducer and activator of transcription factor 6, and allergic asthma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Inflammation and immune regulation by 12/15-lipoxygenases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Dissecting asthma using focused transgenic modeling and functional genomics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

The role of interferon-gamma on immune and allergic responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Let's go mucosal: communication on slippery ground

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

IL-13 receptors and signaling pathways: An evolving web

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Interleukin-13: central mediator of allergic asthma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Mice lacking the IFN-gamma receptor have impaired ability to resolve a lung eosinophilic inflammatory response associated with a prolonged capacity of T cells to exhibit a Th2 cytokine profile.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

A three-tiered view of the role of IgA in mucosal defense

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

IgA-induced eosinophil degranulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

CD4 T-lymphocyte activation in acute severe asthma. Relationship to disease severity and atopic status

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Assessment of the Th1/Th2 paradigm in whole blood in atopy and asthma. Increased IFN-gamma-producing CD8(+) T cells in asthma.

5 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Regulation of 15-lipoxygenase isozymes and mucin secretion by cytokines in cultured normal human bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Expression of 15-lipoxygenase type-1 in human mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Mice lacking 12/15-lipoxygenase have attenuated airway allergic inflammation and remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Requirement for IL-13 independently of IL-4 in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

IgA is a more potent inducer of NADPH oxidase activation and degranulation in blood eosinophils than IgE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumen

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952968

Correlation between IgA antibody and eosinophil cationic protein levels in induced sputum from asthmatic patients

28 October 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F727305

Polyclonal and allergen-induced cytokine responses in adults with asthma: resolution of asthma is associated with normalization of IFN-gamma responses

21 January 2018

1 reference

12 December 2020

Elevated serum interferon-gamma in atopic asthma correlates with increased airways responsiveness and circadian peak expiratory flow variation

1 reference

12 December 2020

Heterogeneity of expression of IgA receptors by human, mouse, and rat eosinophils

1 reference

12 December 2020

Secretory IgA induces antigen-independent eosinophil survival and cytokine production without inducing effector functions

1 reference

12 December 2020

Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies

1 reference

12 December 2020

IFN-gamma attenuates antigen-induced overall immune response in the airway as a Th1-type immune regulatory cytokine

1 reference

12 December 2020

Arachidonic acid 15-lipoxygenase products from human eosinophils

1 reference

12 December 2020

Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

1 reference

12 December 2020

Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma

1 reference

12 December 2020

The effects of nebulized recombinant interferon-gamma in asthmatic airways

1 reference

12 December 2020

IL-13 expression at the sites of allergen challenge in patients with asthma

1 reference

12 December 2020

Cutting Edge: Lipoxin (LX) A4 and Aspirin-Triggered 15-Epi-LXA4 Block Allergen-Induced Eosinophil Trafficking

1 reference

12 December 2020

Il-13 and IFN-gamma: interactions in lung inflammation

1 reference

12 December 2020

Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma

1 reference

12 December 2020

Allergen-induced cytokine production in atopic disease and its relationship to disease severity

1 reference

12 December 2020

American Review of Respiratory Disease

7

141

970

1990

1 reference

4 August 2024

Identifiers

DOI

10.1155/2010/727305

1 reference

31 July 2017

1 reference

31 July 2017

1 reference