(Q36400465)

English

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

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Statements

scholarly article

1 reference

Europe PubMed Central

14 August 2017

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production (English)

1 reference

Europe PubMed Central

14 August 2017

author name string

D Kuperman

1

1 reference

Europe PubMed Central

14 August 2017

B Schofield

2

1 reference

Europe PubMed Central

14 August 2017

M Wills-Karp

3

1 reference

Europe PubMed Central

14 August 2017

M J Grusby

4

1 reference

Europe PubMed Central

14 August 2017

language of work or name

0 references

publication date

1 March 1998

1 reference

Europe PubMed Central

14 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

14 August 2017

187

1 reference

Europe PubMed Central

14 August 2017

939-948

1 reference

Europe PubMed Central

14 August 2017

6

1 reference

Europe PubMed Central

14 August 2017

Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Essential role of Stat6 in IL-4 signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

The potential for recruiting immune responses toward type 1 or type 2 T cell help.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Role of IRS-2 in insulin and cytokine signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Recombinant human interleukin 5 is a selective activator of human eosinophil function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

IL-4 is required to generate and sustain in vivo IgE responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

30 September 2017

Role for neurokinin-2 receptor in interleukin-5-induced airway hyperresponsiveness but not eosinophilia in guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

28 June 2018

Stat6 and Jak1 are common elements in platelet-derived growth factor and interleukin-4 signal transduction pathways in NIH 3T3 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

28 June 2018

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

28 June 2018

Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

28 June 2018

B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

28 June 2018

IL-4 directs the development of Th2-like helper effectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

28 June 2018

Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

21 September 2018

A novel role for murine IL-4 in vivo: induction of MUC5AC gene expression and mucin hypersecretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

21 September 2018

Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

21 September 2018

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

21 September 2018

Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212182

21 September 2018

Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4-dependent pulmonary eosinophil infiltration in a murine model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-derived growth factor and its receptor in lungs from patients with asthma and chronic airflow obstruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 4 receptor: signaling mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 is required for the induction of lung Th2 mucosal immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity of human mast cells based on cytokine content

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-13 expression at the sites of allergen challenge in patients with asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-derived growth factor in asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human interleukin 5 is a selective eosinophil chemoattractant

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between Airway Responsiveness and Serum IgE in Children with Asthma and in Apparently Normal Children

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9500796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.187.6.939

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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0 references

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