(Q34191397)

31 July 2017

Evidence for two sites of superoxide production by mitochondrial NADH-ubiquinone oxidoreductase (complex I). (English)

1 reference

31 July 2017

1

Jason R Treberg

1 reference

31 July 2017

Casey L Quinlan

2

1 reference

ORCID Public Data File 2021

author name string

Martin D Brand

series ordinal

3

1 reference

PubMed ID

21659507

31 July 2017

language of work or name

English

0 references

publication date

8 June 2011

1 reference

Journal of Biological Chemistry

31 July 2017

1 reference

31 July 2017

286

1 reference

31 July 2017

31

1 reference

31 July 2017

27103-27110

1 reference

A model of the proton translocation mechanism of complex I

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production--a correction using glutathione depletion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

The sites and topology of mitochondrial superoxide production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

The production of reactive oxygen species by complex I.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Production of reactive oxygen species by complex I (NADH:ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Generation of superoxide by the mitochondrial Complex I.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Topology of superoxide production from different sites in the mitochondrial electron transport chain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Dependence of H2O2 formation by rat heart mitochondria on substrate availability and donor age.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

On the redox potentials of ubiquinone and cytochrome b in the respiratory chain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Studies on the electron transfer pathway, topography of iron-sulfur centers, and site of coupling in NADH-Q oxidoreductase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoreductase by rotenone, piericidin A, and MPP+

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Localization of the site of oxygen radical generation inside the complex I of heart and nonsynaptic brain mammalian mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Generation of superoxide-radical by the NADH:ubiquinone oxidoreductase of heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Generation of reactive oxygen species by the mitochondrial electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Superoxide and hydrogen peroxide production by Drosophila mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

EPR characterization of ubisemiquinones and iron-sulfur cluster N2, central components of the energy coupling in the NADH-ubiquinone oxidoreductase (complex I) in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Dissociation of superoxide production by mitochondrial complex I from NAD(P)H redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

New insights into the superoxide generation sites in bovine heart NADH-ubiquinone oxidoreductase (Complex I): the significance of protein-associated ubiquinone and the dynamic shifting of generation sites between semiflavin and semiquinone radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

A possible site of superoxide generation in the complex I segment of rat heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.252502

Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149303

Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21659507

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.252502

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

21659507