(Q34195277)

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Understanding large multiprotein complexes: applying a multiple allosteric networks model to explain the function of the Mediator transcription complex

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Europe PubMed Central

PubMed publication ID

31 July 2017

Understanding large multiprotein complexes: applying a multiple allosteric networks model to explain the function of the Mediator transcription complex (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Brian A Lewis

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

1 January 2010

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Europe PubMed Central

PubMed publication ID

31 July 2017

Journal of Cell Science

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Europe PubMed Central

PubMed publication ID

31 July 2017

123

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Europe PubMed Central

PubMed publication ID

31 July 2017

Pt 2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

159-163

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Residues crucial for maintaining short paths in network communication mediate signaling in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Structure of eukaryotic Mediator complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Dynamic regulation of pol II transcription by the mammalian Mediator complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

The mammalian Mediator complex and its role in transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Interactions between subunits of Drosophila Mediator and activator proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

The yeast Mediator complex and its regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Mediator and the mechanism of transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Conformational spread: the propagation of allosteric states in large multiprotein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Ras induces mediator complex exchange on C/EBP beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Uncovering network systems within protein structures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Protein complexes and functional modules in molecular networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

The mediator coactivator complex: functional and physical roles in transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Assortative Mixing in Networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Structure, function, and activator-induced conformations of the CRSP coactivator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Enhancer-promoter specificity mediated by DPE or TATA core promoter motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Lethality and centrality in protein networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Conformational spread in a ring of proteins: a stochastic approach to allostery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Structural organization of yeast and mammalian mediator complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Mediator of Transcriptional Regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Specific structural motifs determine TRAP220 interactions with nuclear hormone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

An activator binding module of yeast RNA polymerase II holoenzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

An activator target in the RNA polymerase II holoenzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Collective dynamics of 'small-world' networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Genetic and physical interactions between yeast RGR1 and SIN4 in chromatin organization and transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

Regulation of HIS4 expression by the Saccharomyces cerevisiae SIN4 transcriptional regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 July 2018

A high resolution protein interaction map of the yeast Mediator complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 October 2018

Distinct conformational states of nuclear receptor-bound CRSP-Med complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 October 2018

Structure and function of CRSP/Med2; a promoter-selective transcriptional coactivator complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 October 2018

Structural determinants of allosteric ligand activation in RXR heterodimers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 October 2018

Network biology: understanding the cell's functional organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 October 2018

Evolutionarily conserved pathways of energetic connectivity in protein families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 October 2018

Network Analysis of Protein Structures Identifies Functional Residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954244

28 October 2018

Conserved structures of mediator and RNA polymerase II holoenzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small-world network approach to identify key residues in protein-protein interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly of a Mediator/TFIID/TFIIA Complex Bypasses the Need for an Activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1242/JCS.057216

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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