(Q34195636)

31 July 2017

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title

From transcription to activation: how group A streptococcus, the flesh-eating pathogen, regulates SpeB cysteine protease production (English)

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31 July 2017

2

James M Musser

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31 July 2017

Ronan K Carroll

1

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31 July 2017

language of work or name

English

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publication date

24 June 2011

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31 July 2017

published in

Molecular Microbiology

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31 July 2017

volume

81

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31 July 2017

issue

3

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31 July 2017

page(s)

588-601

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Absence of a cysteine protease effect on bacterial virulence in two murine models of human invasive group A streptococcal infection

31 July 2017

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Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection

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EndoS and SpeB from Streptococcus pyogenes inhibit immunoglobulin-mediated opsonophagocytosis

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SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines

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A PROTEOLYTIC ENZYME PRODUCED BY GROUP A STREPTOCOCCI WITH SPECIAL REFERENCE TO ITS EFFECT ON THE TYPE-SPECIFIC M ANTIGEN.

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Cleavage of antigen-bound immunoglobulin G by SpeB contributes to streptococcal persistence in opsonizing blood

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Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling

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Streptococcal cysteine proteinase releases kinins: a virulence mechanism

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A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence

21 January 2018

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Streptococcal pyrogenic exotoxin B cleaves human S-adenosylhomocysteine hydrolase and induces hypermethioninemia

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Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: An integrin-binding cysteine protease

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SpeB-Spi: a novel protease-inhibitor pair from Streptococcus pyogenes

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Inverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection cases

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A naturally occurring Rgg variant in serotype M3 Streptococcus pyogenes does not activate speB expression due to altered specificity of DNA binding

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Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes

21 January 2018

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A conserved Streptococcus pyogenes extracellular cysteine protease cleaves human fibronectin and degrades vitronectin

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CcpA and LacD.1 affect temporal regulation of Streptococcus pyogenes virulence genes

21 January 2018

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Group A streptococcal RofA-type global regulators exhibit a strain-specific genomic presence and regulation pattern

21 January 2018

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Degradation of complement 3 by streptococcal pyrogenic exotoxin B inhibits complement activation and neutrophil opsonophagocytosis

21 January 2018

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Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a model for in vivo gene expression

21 January 2018

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A novel adaptation of aldolase regulates virulence in Streptococcus pyogenes

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Trigger factor-mediated prolyl isomerization influences maturation of the Streptococcus pyogenes cysteine protease

21 January 2018

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A role for trigger factor and an rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes

21 January 2018

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Identification and characterization of bicistronic speB and prsA gene expression in the group A Streptococcus

21 January 2018

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vfr, a novel locus affecting cysteine protease production in Streptococcus pyogenes

21 January 2018

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Linking the nutritional status of Streptococcus pyogenes to alteration of transcriptional gene expression: the action of CodY and RelA.

21 January 2018

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Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule.

21 January 2018

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TheluxSGene ofStreptococcus pyogenesRegulates Expression of Genes That Affect Internalization by Epithelial Cells

21 January 2018

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Identification of a novel maturation mechanism and restricted substrate specificity for the SspB cysteine protease of Staphylococcus aureus.

21 January 2018

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21 January 2018

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21 January 2018

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Substrate specificity of the streptococcal cysteine protease

21 January 2018

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21 January 2018

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21 January 2018

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The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease

21 January 2018

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Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production

21 January 2018

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What is the size of the group A streptococcal vir regulon? The Mga regulator affects expression of secreted and surface virulence factors

21 January 2018

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Cysteine protease SpeB expression in group A streptococci is influenced by the nutritional environment but SpeB does not contribute to obtaining essential nutrients

21 January 2018

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Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases.

21 January 2018

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Inactivation of the group A Streptococcus regulator srv results in chromosome wide reduction of transcript levels, and changes in extracellular levels of Sic and SpeB

21 January 2018

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Defining the Mga regulon: Comparative transcriptome analysis reveals both direct and indirect regulation by Mga in the group A streptococcus.

21 January 2018

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Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07709.X

Staphostatins resemble lipocalins, not cystatins in fold

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07709.X

Growth characteristics of and virulence factor production by group A Streptococcus during cultivation in human saliva

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07709.X

A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07709.X

A natural variant of the cysteine protease virulence factor of group A Streptococcus with an arginine-glycine-aspartic acid (RGD) motif preferentially binds human integrins alphavbeta3 and alphaIIbbeta3.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07709.X

Solution Structure and Backbone Dynamics of Streptopain: INSIGHT INTO DIVERSE SUBSTRATE SPECIFICITY

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2011.07709.X

10.1111/J.1365-2958.2011.07709.X

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference