(Q34197593)

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Solubility at the molecular level: development of a critical aggregation concentration (CAC) assay for estimating compound monomer solubility

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Solubility at the molecular level: development of a critical aggregation concentration (CAC) assay for estimating compound monomer solubility (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Jie Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Edmund Matayoshi

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

publication date

16 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

29

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1745-1754

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Biological assay challenges from compound solubility: strategies for bioassay optimization

1 reference

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21 January 2018

High throughput solubility measurement in drug discovery and development

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

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A high-throughput screen for aggregation-based inhibition in a large compound library

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

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Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

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Stoichiometry and physical chemistry of promiscuous aggregate-based inhibitors

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https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

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A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

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https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

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Nonleadlikeness and leadlikeness in biochemical screening

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Comparison of chromatographic and spectroscopic methods used to rank compounds for aqueous solubility

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Automated robotic liquid handling/laser-based nephelometry system for high throughput measurement of kinetic aqueous solubility

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Comparison of nephelometric, UV-spectroscopic, and HPLC methods for high-throughput determination of aqueous drug solubility in microtiter plates

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

In vitro solubility assays in drug discovery

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Alkyl glycoside detergents: synthesis and applications to the study of membrane proteins

1 reference

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21 January 2018

Drugs as materials: valuing physical form in drug discovery

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Aqueous solubility of crystalline and amorphous drugs: Challenges in measurement

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

21 January 2018

Confocal light absorption and scattering spectroscopic microscopy.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0730-8

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Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin

1 reference

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Background rejection and signal-to-noise optimization in confocal and alternative fluorescence microscopes

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The Scattering of Light and the Radial Distribution Function of High Polymer Solutions

1 reference

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21 January 2018

Rationale and benefit of using high throughput solubility screens in drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/22422319

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Evaluation of amorphous solid dispersion properties using thermal analysis techniques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22422319

12 December 2020

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Equilibrium drug solubility measurements in 96-well plates reveal similar drug solubilities in phosphate buffer pH 6.8 and human intestinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22422319

12 December 2020

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High throughput solubility measurement with automated polarized light microscopy analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22422319

12 December 2020

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Evaluation of the chemiluminescent nitrogen detector for solubility determinations to support drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/22422319

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Identification of promiscuous small molecule activators in high-throughput enzyme activation screens

1 reference

https://pubmed.ncbi.nlm.nih.gov/22422319

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High-speed solubility screening assay using ultra-performance liquid chromatography/mass spectrometry in drug discovery

1 reference

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Identifiers

10.1007/S11095-012-0730-8

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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