(Q34203441)

31 July 2017

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title

Role and regulation of the thrombin receptor (PAR-1) in human melanoma (English)

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31 July 2017

Carmen Tellez

1

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31 July 2017

Menashe Bar-Eli

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 May 2003

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31 July 2017

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31 July 2017

22

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31 July 2017

20

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31 July 2017

3130-3137

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206453

31 July 2017

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cites work

Expression of AP-2 transcription factor and of its downstream target genes c-kit, E-cadherin and p21 in human cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Gene regulation in melanoma progression by the AP-2 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

The genomic structure of the human AP-2 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Angiogenesis in cancer and other diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Regulation of K3 keratin gene transcription by Sp1 and AP-2 in differentiating rabbit corneal epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin Induces Production of Growth Factors from Aortic Smooth Muscle Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

The biology of prothrombin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin receptor overexpression in malignant and physiological invasion processes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Tumor cell invasion is promoted by activation of protease activated receptor-1 in cooperation with the alpha vbeta 5 integrin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Regulation of thrombin generation and functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transplacental carcinogenesis by stilbestrol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcriptional activation by Myc is under negative control by the transcription factor AP-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Promoter elements of the mouse acetylcholinesterase gene. Transcriptional regulation during muscle differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Ultraviolet-A-induced transactivation of the vascular endothelial growth factor gene in HaCaT keratinocytes is conveyed by activator protein-2 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transforming growth factor-alpha-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Cellular consequences of thrombin-receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Upstream promoter element of the human metallothionein-IIA gene can act like an enhancer element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Role of thrombin receptor in breast cancer invasiveness

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Redox modulation of AP-2 DNA binding activity in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

CREB and its associated proteins act as survival factors for human melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Inhibition of tumor growth and metastasis of human melanoma by intracellular anti-ATF-1 single chain Fv fragment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

The repressive function of AP2 transcription factor on the hepatocyte growth factor gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Sequential repression and activation of the CCAAT enhancer-binding protein-alpha (C/EBPalpha ) gene during adipogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Downregulation of transcription factor AP-2 predicts poor survival in stage I cutaneous malignant melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin receptor activation results in calcium signaling and protein kinase C-dependent stimulation of DNA synthesis in HEp-2g laryngeal carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Tumor angiogenesis: past, present and the near future

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Microphthalmia transcription factor. A sensitive and specific melanocyte marker for MelanomaDiagnosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcription factor AP2 and its role in epidermal-specific gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Subcutaneous heparin treatment increases survival in small cell lung cancer. "Petites Cellules" Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Cloning and identification of regulatory sequences of the human thrombin receptor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Expression of protease-activated receptor 1 in oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

From natural to synthetic multisite thrombin inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Molecular events in melanoma development and progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

The use of heparin for treating human malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Treatment of cancer with anticoagulants: rationale in the treatment of melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Angiogenesis and G-protein-coupled receptors: signals that bridge the gap.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Characterization of functional thrombin receptors in human pancreatic tumor cells (MIA PACA-2)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Expression and transcriptional activity of AP-1, CRE, and URE binding proteins in B16 mouse melanoma subclones.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcription factor AP-2 essential for cranial closure and craniofacial development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin stimulates the expression of PDGF in lung epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Treatment with coumarin to prevent or delay recurrence of malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin stimulates production of interleukin-8 in human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin increases the metastatic potential of tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin enhances tumor cell adhesive and metastatic properties via increased alpha IIb beta 3 expression on the cell surface

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Malignant melanoma. Interaction with coagulation and fibrinolysis pathways in situ

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Dominant-negative CREB inhibits tumor growth and metastasis of human melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Transcriptional regulation of the 5' proximal promoter of the human manganese superoxide dismutase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

A family of AP-2 proteins down-regulate manganese superoxide dismutase expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Thrombin induces the activation of progelatinase A in vascular endothelial cells. Physiologic regulation of angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206453

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206453

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Dimensions Publication ID

31 July 2017

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1 reference