(Q34204885)

31 July 2017

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title

Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension (English)

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31 July 2017

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essential hypertension

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1

O Smithies

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31 July 2017

N Maeda

2

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PubMed ID

7777495

31 July 2017

language of work or name

English

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publication date

1 June 1995

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

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31 July 2017

92

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31 July 2017

5266-5272

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31 July 2017

12

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The pathogenesis of atherosclerosis: a perspective for the 1990s

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Angiotensinogen-deficient mice with hypotension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Regulation of blood pressure by the type 1A angiotensin II receptor gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Genetic control of blood pressure and the angiotensinogen locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

The mouse Rn locus: S allele of the renin regulator gene results from a single structural gene duplication.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Lipoprotein mutations in pigs are associated with elevated plasma cholesterol and atherosclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

A receptor-mediated pathway for cholesterol homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Apolipoprotein E deficiency with a depressed mRNA of normal size.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

Molecular basis of human hypertension: role of angiotensinogen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41675

A DNA polymorphism, consistent with gene duplication, correlates with high renin levels in the mouse submaxillary gland

5 July 2018

1 reference

12 December 2020

Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia

1 reference

12 December 2020

Variation in susceptibility to atherosclerosis among inbred strains of mice

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12 December 2020

A young type III hyperlipoproteinemic patient associated with apolipoprotein E deficiency

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12 December 2020

Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice

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12 December 2020

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

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12 December 2020

Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression

1 reference

12 December 2020

Diet-induced hypercholesterolemia and atherosclerosis in heterozygous apolipoprotein E-deficient mice

1 reference

12 December 2020

Type III hyperlipoproteinemia associated with apolipoprotein E deficiency

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.92.12.5266

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31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

7777495