(Q34205523)

31 July 2017

title

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans (English)

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Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

31 July 2017

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corrigendum / erratum

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author

Massimo Mangino

17

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31 July 2017

33

Nicole Soranzo

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Eleftheria Zeggini

32

Eleftheria Zeggini

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Valentina Iotchkova

Valentina Iotchkova

10

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Massimiliano Cocca

Massimiliano Cocca

11

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Amadou Gaye

Amadou Gaye

21

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Shane McCarthy

Shane McCarthy

14

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Marta Futema

Marta Futema

8

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Giovanni Malerba

Giovanni Malerba

5

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Klaudia Walter

Klaudia Walter

2

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Cristina Menni

Cristina Menni

18

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Philippa Talmud

Philippa J Talmud

25

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Stephen E Humphries

Steve E Humphries

31

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Nicholas J. Timpson

Nicholas J Timpson

1

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George Davey Smith

George Davey Smith

28

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Richard M. Durbin

29

Richard Durbin

1 reference

31 July 2017

7

Lu Chen

1 reference

31 July 2017

13

Yasin Memari

1 reference

31 July 2017

15

Petr Danecek

1 reference

31 July 2017

20

Susan M Ring

1 reference

31 July 2017

27

Tim D Spector

1 reference

31 July 2017

22

George Dedoussis

1 reference

31 July 2017

16

Dawn Muddyman

1 reference

31 July 2017

Josine L Min

3

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31 July 2017

Ioanna Tachmazidou

4

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31 July 2017

So-Youn Shin

6

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31 July 2017

Lorraine Southam

9

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31 July 2017

Jie Huang

12

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31 July 2017

John R B Perry

19

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31 July 2017

Aliki-Eleni Farmaki

23

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31 July 2017

Paul Burton

24

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31 July 2017

Giovanni Gambaro

26

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31 July 2017

J Brent Richards

30

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31 July 2017

UK1OK Consortium Members

34

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31 July 2017

UK1OK Consortium Members

35

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31 July 2017

language of work or name

English

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publication date

16 September 2014

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31 July 2017

published in

Nature Communications

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31 July 2017

volume

5

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31 July 2017

page(s)

4871

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A general approach for haplotype phasing across the full spectrum of relatedness

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

5 July 2018

1 reference

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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

5 July 2018

1 reference

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Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

5 July 2018

1 reference

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A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Remnant cholesterol as a cause of ischemic heart disease: evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment

5 July 2018

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Associations of maternal 25-hydroxyvitamin D in pregnancy with offspring cardiovascular risk factors in childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children

5 July 2018

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Discovery and refinement of loci associated with lipid levels

5 July 2018

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Common variants associated with plasma triglycerides and risk for coronary artery disease

5 July 2018

1 reference

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Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia

5 July 2018

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5 July 2018

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The Genotype-Tissue Expression (GTEx) project

5 July 2018

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Genes contributing to pain sensitivity in the normal population: an exome sequencing study.

5 July 2018

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Genome-wide efficient mixed-model analysis for association studies

5 July 2018

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Antisense oligonucleotides for the treatment of dyslipidaemia

5 July 2018

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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

5 July 2018

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Cohort profile: the 'children of the 90s'—the index offspring of the Avon Longitudinal Study of Parents and Children

5 July 2018

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Cohort Profile: TwinsUK and healthy ageing twin study

5 July 2018

1 reference

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The mystery of missing heritability: Genetic interactions create phantom heritability

5 July 2018

1 reference

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A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Rare-variant association testing for sequencing data with the sequence kernel association test

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

A framework for variation discovery and genotyping using next-generation DNA sequencing data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Lipid parameters for measuring risk of cardiovascular disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

GCTA: a tool for genome-wide complex trait analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Integrating common and rare genetic variation in diverse human populations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Biological, clinical and population relevance of 95 loci for blood lipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Genotype imputation for genome-wide association studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

GWAMA: software for genome-wide association meta-analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Fast and accurate long-read alignment with Burrows-Wheeler transform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Major lipids, apolipoproteins, and risk of vascular disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

PLINK: a tool set for whole-genome association and population-based linkage analyses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Principal components analysis corrects for stratification in genome-wide association studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Mendelian randomization: prospects, potentials, and limitations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Complex genetic contribution of the Apo AI-CIII-AIV gene cluster to familial combined hyperlipidemia. Identification of different susceptibility haplotypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Isolation and sequence analysis of the human apolipoprotein CIII gene and the intergenic region between the apo AI and apo CIII genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Human apolipoprotein CIII gene expression is regulated by positive and negative cis-acting elements and tissue-specific protein factors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Promoter elements and factors required for hepatic and intestinal transcription of the human ApoCIII gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Changing relative proportions of apolipoproteins CII and CIII of very low density lipoproteins in hypertriglyceridaemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5871

Do total and high density lipoprotein cholesterol and triglycerides act independently in the prediction of ischemic heart disease? Ten-year follow-up of Caerphilly and Speedwell Cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5871

Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5871

Genetic epidemiology: an 'enlightened narrative'?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5871

Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: effects on LDL-cholesterol and apolipoproteins B and C-III.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167609

Apolipoproteins C-II and C-III metabolism in hypertriglyceridemic patients. Effect of a drastic triglyceride reduction by combined diet restriction and fenofibrate administration

28 October 2018

1 reference

12 December 2020

A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia

1 reference

12 December 2020

The apolipoprotein A-I/C-III/A-IV gene cluster: ApoC-III and ApoA-IV expression is regulated by two common enhancers

1 reference

12 December 2020

The sex-specific genetic architecture of quantitative traits in humans

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS5871

1 reference

Dimensions Publication ID

31 July 2017

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31 July 2017

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