(Q34205937)

31 July 2017

title

Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis (English)

1 reference

31 July 2017

6

Georg W Bornkamm

1 reference

31 July 2017

Lisa M Nilsson

1

1 reference

31 July 2017

Tacha Zi Plym Forshell

2

1 reference

31 July 2017

Sara Rimpi

3

1 reference

31 July 2017

Christiane Kreutzer

4

1 reference

31 July 2017

Walter Pretsch

5

1 reference

31 July 2017

Jonas A Nilsson

7

1 reference

31 July 2017

publication date

15 March 2012

1 reference

31 July 2017

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31 July 2017

volume

8

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31 July 2017

issue

3

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31 July 2017

page(s)

e1002573

1 reference

Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

15 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

5 July 2018

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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

5 July 2018

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MYC-induced cancer cell energy metabolism and therapeutic opportunities

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A role for E2F activities in determining the fate of Myc-induced lymphomagenesis

5 July 2018

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LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

5 July 2018

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Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine

5 July 2018

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5 July 2018

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Distinct thresholds govern Myc's biological output in vivo

5 July 2018

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ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

5 July 2018

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5 July 2018

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Targeting aspartate aminotransferase in breast cancer

5 July 2018

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Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial

5 July 2018

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Cancer cell metabolism: Warburg and beyond

5 July 2018

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Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice

5 July 2018

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The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry

5 July 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

5 July 2018

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Myc deletion rescues Apc deficiency in the small intestine

5 July 2018

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Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

5 July 2018

1 reference

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Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

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5 July 2018

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A role for K-ras in conferring resistance to the MEK inhibitor, CI-1040.

5 July 2018

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Multifaceted roles of glycolytic enzymes.

5 July 2018

1 reference

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Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

5 July 2018

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5 July 2018

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S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression

5 July 2018

1 reference

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A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism

5 July 2018

1 reference

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Burkitt lymphoma in the mouse.

5 July 2018

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5 July 2018

The Hallmarks of Cancer

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INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

A unique glucose-dependent apoptotic pathway induced by c-Myc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

Cloning, sequencing and expression of rat liver 3-phosphoglycerate dehydrogenase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

HER-2/neu signal transduction in human breast and ovarian cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

The ornithine decarboxylase gene is a transcriptional target of c-Myc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

A mutation affecting the lactate dehydrogenase locus Ldh-1 in the mouse. II. Mechanism of the LDH-A deficiency associated with hemolytic anemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

Phosphotyrosine-containing lactate dehydrogenase is restricted to the nuclei of PC12 pheochromocytoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

Analysis of genomic targets reveals complex functions of MYC.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002573

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002573

Chemoprevention of mammary carcinogenesis in a transgenic mouse model by alpha-difluoromethylornithine (DFMO) in the diet is associated with decreased cyclin D1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002573

Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002573

Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002573

Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002573

Chemopreventive effect of difluoromethylornithine (DFMO) on mouse skin squamous cell carcinomas induced by benzo(a)pyrene.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

c-Myc induces the expression and activity of ornithine decarboxylase.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305401

Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos

28 October 2018

1 reference

12 December 2020

Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice

1 reference

12 December 2020

A binding assay for serine hydroxymethyltransferase

1 reference

12 December 2020

Genomic instability and apoptosis are frequent in p53 deficient young mice

1 reference

12 December 2020

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1002573

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference