(Q34206982)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Ethanol-induced modulation of hepatocellular extracellular signal-regulated kinase-1/2 activity via 4-hydroxynonenal (English)

1 reference

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21 December 2019

1

1 reference

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21 December 2019

author name string

Benjamin J Stewart

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Dennis R Petersen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

15 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

21 December 2019

published in

1 reference

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21 December 2019

volume

282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

1925-1937

1 reference

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describes a project that uses

21 December 2019

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2956423/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Mechanisms of glutamate cysteine ligase (GCL) induction by 4-hydroxynonenal

5 July 2018

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Inhibition of Hsp72-mediated protein refolding by 4-hydroxy-2-nonenal

5 July 2018

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Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.

5 July 2018

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4-Hydroxynonenal regulates 26S proteasomal degradation of alcohol dehydrogenase.

5 July 2018

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MAP kinase signaling in diverse effects of ethanol

5 July 2018

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Immunohistochemical characterization of hepatic malondialdehyde and 4-hydroxynonenal modified proteins during early stages of ethanol-induced liver injury.

5 July 2018

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Molecular basis of enzyme inactivation by an endogenous electrophile 4-hydroxy-2-nonenal: identification of modification sites in glyceraldehyde-3-phosphate dehydrogenase

5 July 2018

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Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal

5 July 2018

1 reference

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Role of malondialdehyde-acetaldehyde adducts in liver injury

5 July 2018

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5 July 2018

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Distribution of ethanol-induced protein adducts in vivo: relationship to tissue injury

5 July 2018

1 reference

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Models of alcoholic liver disease in rodents: a critical evaluation

5 July 2018

1 reference

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IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal

5 July 2018

1 reference

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4-Hydroxynonenal in the pathomechanisms of oxidative stress

5 July 2018

1 reference

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

5 July 2018

1 reference

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Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation

5 July 2018

1 reference

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Ebselen prevents early alcohol-induced liver injury in rats

5 July 2018

1 reference

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Alcohol-induced generation of lipid peroxidation products in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

HNE interacts directly with JNK isoforms in human hepatic stellate cells

5 July 2018

1 reference

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Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Biogenic 4-hydroxy-2-nonenal activates transcription factor AP-1 but not NF-kappa B in cells of the macrophage lineage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

In situ detection of lipid peroxidation in chronic hepatitis C: correlation with pathological features

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

In situ detection of lipid peroxidation by-products in chronic liver diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

AP-1 function and regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

4-Hydroxynonenal-induced cell death in murine alveolar macrophages.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Role of aldehyde metabolizing enzymes in mediating effects of aldehyde products of lipid peroxidation in liver cells.

5 July 2018

1 reference

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Lipid peroxidation in rats chronically fed ethanol

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

The mitogen-activated protein kinases, ERK1 and ERK2.

5 July 2018

1 reference

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The regulation of AP-1 activity by mitogen-activated protein kinases

5 July 2018

1 reference

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Experimental liver cirrhosis induced by alcohol and iron

5 July 2018

1 reference

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Inhibition of liver regeneration by chronic alcohol administration

5 July 2018

1 reference

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Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Ethanol-induced lipid peroxidation and oxidative stress in extrahepatic tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: association of lipid peroxidation with liver fibrogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Control of transcription factors by signal transduction pathways: the beginning of the end

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Effects of diffusible products of peroxidation of rat liver microsomal lipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Modification of heat shock protein 90 by 4-hydroxynonenal in a rat model of chronic alcoholic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

In vivo activation and in situ BDNF-stimulated nuclear translocation of mitogen-activated/extracellular signal-regulated protein kinase is inhibited by ethanol in the developing rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Acute ethanol inhibits extracellular signal-regulated kinase, protein kinase B, and adenosine 3':5'-cyclic monophosphate response element binding protein activity in an age- and brain region-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Alpha,beta-unsaturated aldehydes increase glutathione S-transferase mRNA and protein: correlation with activation of the antioxidant response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

4-hydroxynonenal decreases interleukin-6 expression and protein production in primary rat Kupffer cells by inhibiting nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Effects of chronic ethanol treatment on the angiotensin II-mediated p42/p44 mitogen-activated protein kinase and phosphorylase a activation in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal-treated sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

Malondialdehyde modification of proteins in vitro is enhanced in the presence of acetaldehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

The lipid peroxidation end product 4-hydroxy-2,3-nonenal up-regulates transforming growth factor beta1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956423

Effect of upright posture and physical exercise on endogenous neurohormonal systems in cirrhotic patients with sodium retention and normal supine plasma renin, aldosterone, and norepinephrine levels*1

28 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610602200

4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules

21 January 2018

1 reference

12 December 2020

4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells

1 reference

12 December 2020

Inhibition of hepatic regeneration in rats by acute and chronic ethanol intoxication

1 reference

12 December 2020

Reaction of malondialdehyde with deoxyribonucleosides in the presence of acetaldehyde

1 reference

12 December 2020

Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease

1 reference

12 December 2020

4-Hydroxynonenal mimics ozone-induced modulation of macrophage function ex vivo

1 reference

12 December 2020

4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization

1 reference

12 December 2020

4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death

1 reference

12 December 2020

4-Hydroxynonenal induces oxidative stress and death of cultured spinal cord neurons

1 reference

12 December 2020

Oxidative stress in alcoholic liver injury

1 reference

12 December 2020

Co-metabolism of ethanol, ethanol-derived acetaldehyde, and 4-hydroxynonenal in isolated rat hepatocytes

1 reference

12 December 2020

Prooxidant-initiated lipid peroxidation in isolated rat hepatocytes: detection of 4-hydroxynonenal- and malondialdehyde-protein adducts

1 reference

12 December 2020

Induction of rat aortic smooth muscle cell growth by the lipid peroxidation product 4-hydroxy-2-nonenal

1 reference

12 December 2020

A new oral low-carbohydrate alcohol liquid diet producing liver lesions: a preliminary account

1 reference

12 December 2020

Ethanol inhibits mitogen activated protein kinase activity and growth of vascular smooth muscle cells in vitro

1 reference

12 December 2020

Mechanism of inhibition of rat liver class 2 ALDH by 4-hydroxynonenal

1 reference

12 December 2020

Studies on the mechanism of formation of 4-hydroxynonenal during microsomal lipid peroxidation

1 reference

12 December 2020

Inhibition of rat hepatic mitochondrial aldehyde dehydrogenase-mediated acetaldehyde oxidation by trans-4-hydroxy-2-nonenal

1 reference

12 December 2020

Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction

1 reference

12 December 2020

Accumulation of aldehydic lipid peroxidation products during postanoxic reoxygenation of isolated rat hepatocytes

1 reference

12 December 2020

Stimulation of HeLa cell growth by physiological concentrations of 4-hydroxynonenal

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M610602200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107949%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference