(Q34208784)

31 July 2017

title

The tumour suppressor Fhit positively regulates MHC class I expression on cancer cells (English)

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31 July 2017

6

Federico Garrido

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31 July 2017

Irene Romero

1

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31 July 2017

Marisol Martinez

2

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31 July 2017

Cristina Garrido

3

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31 July 2017

Antonia Collado

4

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31 July 2017

Ignacio Algarra

5

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31 July 2017

Angel M Garcia-Lora

7

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31 July 2017

publication date

23 May 2012

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31 July 2017

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31 July 2017

volume

227

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31 July 2017

issue

3

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31 July 2017

page(s)

367-379

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Immune surveillance of tumors

31 July 2017

cites work

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Natural innate and adaptive immunity to cancer

21 January 2018

1 reference

Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment

21 January 2018

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The three Es of cancer immunoediting

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Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

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Human T cell responses against melanoma

21 January 2018

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A listing of human tumor antigens recognized by T cells: March 2004 update

21 January 2018

1 reference

Recent advances in antigen processing and presentation

21 January 2018

1 reference

MHC antigens and tumor escape from immune surveillance

21 January 2018

1 reference

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

21 January 2018

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HLA class I antigen abnormalities and immune escape by malignant cells.

21 January 2018

1 reference

MHC class I antigens, immune surveillance, and tumor immune escape.

21 January 2018

1 reference

Distribution of HLA class I altered phenotypes in colorectal carcinomas: high frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21.

21 January 2018

1 reference

Haplotype loss of HLA class I antigen as an escape mechanism from immune attack in lung cancer

21 January 2018

1 reference

Immune selection of hot-spot beta 2-microglobulin gene mutations, HLA-A2 allospecificity loss, and antigen-processing machinery component down-regulation in melanoma cells derived from recurrent metastases following immunotherapy

21 January 2018

1 reference

beta2-Microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.

21 January 2018

1 reference

A new beta 2 microglobulin mutation found in a melanoma tumor cell line

21 January 2018

1 reference

Complete loss of HLA class I antigen expression on melanoma cells: a result of successive mutational events.

21 January 2018

1 reference

The known unknowns of antigen processing and presentation.

21 January 2018

1 reference

Epigenetic control of the immune escape mechanisms in malignant carcinomas

21 January 2018

1 reference

A weakly tumorigenic phenotype with high MHC class-I expression is associated with high metastatic potential after surgical removal of the primary murine fibrosarcoma.

21 January 2018

1 reference

Immunoselection by T lymphocytes generates repeated MHC class I-deficient metastatic tumor variants

21 January 2018

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MHC class I-deficient metastatic tumor variants immunoselected by T lymphocytes originate from the coordinated downregulation of APM components.

21 January 2018

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Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines

21 January 2018

1 reference

Alterations of HLA class I expression in human melanoma xenografts in immunodeficient mice occur frequently and are associated with higher tumorigenicity.

21 January 2018

1 reference

Identification of human cancers deficient in antigen processing

21 January 2018

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Coordinated downregulation of the antigen presentation machinery and HLA class I/beta2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer

21 January 2018

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Loss of FHIT expression in transitional cell carcinoma of the urinary bladder

21 January 2018

1 reference

Common fragile sites are characterized by histone hypoacetylation

21 January 2018

1 reference

Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch

21 January 2018

1 reference

Fhit regulates invasion of lung tumor cells

21 January 2018

1 reference

FHIT is up-regulated by inflammatory stimuli and inhibits prostaglandin E2-mediated cancer progression

21 January 2018

1 reference

FHIT gene therapy prevents tumor development in Fhit-deficient mice.

21 January 2018

1 reference

The tumor spectrum in FHIT-deficient mice

21 January 2018

1 reference

Potential cancer therapy with the fragile histidine triad gene: review of the preclinical studies

21 January 2018

1 reference

Diadenosines as FHIT-ness instructors

21 January 2018

1 reference

Total loss of HLA class I expression on a melanoma cell line after growth in nude mice in absence of autologous antitumor immune response.

21 January 2018

1 reference

MHC class I molecules act as tumor suppressor genes regulating the cell cycle gene expression, invasion and intrinsic tumorigenicity of melanoma cells.

21 January 2018

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The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control

21 January 2018

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Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition

21 January 2018

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AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

21 January 2018

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HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway.

21 January 2018

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Down regulation of major histocompatibility complex class I expression in mammary carcinoma of HER-2/neu transgenic mice.

21 January 2018

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Inverse correlation of HER2 with MHC class I expression on oesophageal squamous cell carcinoma

21 January 2018

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T cell recognition of HLA-A2 restricted tumor antigens is impaired by the oncogene HER2.

21 January 2018

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FHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells

21 January 2018

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Fhit expression protects against HER2-driven breast tumor development: unraveling the molecular interconnections

21 January 2018

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Fhit is a physiological target of the protein kinase Src

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4029

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31 July 2017

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