(Q34208914)

English

Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

based on heuristic

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Kurunthachalam Kannan

7

object named as

Kurunthachalam Kannan

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Fang Xie

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Xin Zhou

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Melissa Behr

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Cheng Fang

4

1 reference

Europe PubMed Central

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31 July 2017

Yuichi Horii

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Jun Gu

6

1 reference

Europe PubMed Central

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31 July 2017

Xinxin Ding

8

1 reference

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31 July 2017

publication date

16 September 2010

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31 July 2017

Toxicology and Applied Pharmacology

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Europe PubMed Central

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31 July 2017

249

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Europe PubMed Central

PubMed publication ID

31 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

101-106

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Regulation of the cytochrome P450 2A genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Methimazole-induced damage in the olfactory mucosa: effects on ultrastructure and glutathione levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Characterization of human CYP2G genes: widespread loss-of-function mutations and genetic polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Intraperitoneal administration of coumarin causes tissue-selective depletion of cytochromes P450 and cytotoxicity in the olfactory mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Distribution of microsomal epoxide hydrolase and glutathione S-transferase in the rat olfactory mucosa: relevance to distribution of lesions caused by systemically-administered olfactory toxicants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Irreversible binding and toxicity of the herbicide dichlobenil (2,6-dichlorobenzonitrile) in the olfactory mucosa of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

5 July 2018

Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

28 October 2018

Determination of 112 halogenated pesticides using gas chromatography/mass spectrometry with selected ion monitoring

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

28 October 2018

In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

28 October 2018

Differential effects of olfactory toxicants on olfactory regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

28 October 2018

Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956786

28 October 2018

Histopathologic examination of the rat nasal cavity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of glutathione-modulating agents on the covalent binding and toxicity of dichlobenil in the mouse olfactory mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic activation of the olfactory toxicant, dichlobenil, in rat olfactory microsomes: comparative studies with p-nitrophenol

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism-dependent toxicity of methimazole in the olfactory nasal mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological and histological recovery of the olfactory mucosa of the frog after a dichlobenil injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic activation of 2,6-dichlorobenzonitrile, an olfactory-specific toxicant, by rat, rabbit, and human cytochromes P450

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Mouse Model with Liver-Specific Deletion and Global Suppression of the NADPH-Cytochrome P450 Reductase Gene: Characterization and Utility for in Vivo Studies of Cyclophosphamide Disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of small intestinal cytochromes p450 in the bioavailability of oral nifedipine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TAAP.2010.09.003

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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