(Q34217637)

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Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20473920%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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Europe PubMed Central

Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20473920%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

literature review

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inferred from title

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2 February 2020

Edward Giovannucci

6

object named as

Edward L Giovannucci

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2 February 2020

Jeffrey A Meyerhardt

5

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Jeffrey A Meyerhardt

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2 February 2020

Charles S. Fuchs

7

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Charles S Fuchs

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2 February 2020

Katsuhiko Nosho

2

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Katsuhiko Nosho

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2 February 2020

3

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Yoshifumi Baba

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2 February 2020

4

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Mami Cantor

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2 February 2020

author name string

Kaori Shima

1

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2 February 2020

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1 March 2011

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2 February 2020

International Journal of Cancer

1 reference

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2 February 2020

128

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2 February 2020

5

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Europe PubMed Central

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2 February 2020

1080-1094

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20473920%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Tumor suppressor mechanisms in immune aging

1 reference

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5 July 2018

Utility of p16 immunohistochemistry for the identification of Lynch syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

CpG island methylator phenotype (CIMP) in cancer: causes and implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

p16INK4a gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Molecular classification and correlates in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Cellular senescence in cancer and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Aspirin and the risk of colorectal cancer in relation to the expression of COX-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Comethylation of p16 and MGMT genes in colorectal carcinoma: correlation with clinicopathological features and prognostic value

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

p16(Ink4a) inhibits histologic progression and angiogenic signaling in min colon tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Sensitive sequencing method for KRAS mutation detection by Pyrosequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Low microsatellite instability is associated with poor prognosis in stage C colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Systematic review of microsatellite instability and colorectal cancer prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Expressing patterns of p16 and CDK4 correlated to prognosis in colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

A gene hypermethylation profile of human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

CpG island methylator phenotype in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

5 July 2018

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Influence of methylated p15 and p16 genes on clinicopathological features in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Profiling markers of prognosis in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite Instability

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

The MTHFR C677T and DeltaDNMT3B C-149T polymorphisms confer different risks for right- and left-sided colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Expression and prognostic significance of APAF-1, caspase-8 and caspase-9 in stage II/III colon carcinoma: caspase-8 and caspase-9 is associated with poor prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

28 October 2018

Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

28 October 2018

CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

28 October 2018

Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

28 October 2018

K-ras and p16 aberrations confer poor prognosis in human colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958235

28 October 2018

Colorectal Cancer Risk Is Not Associated with Increased Levels of Homozygosity in a Population from the United Kingdom

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Hypermethylation of the p16 Gene in Sporadic T3N0M0 Stage Colorectal Cancers: Association with DNA Replication Error and Shorter Survival

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

p16 Gene Methylation in Colorectal Tumors: Correlation with Clinicopathological Features and Prognostic Value

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25432

21 January 2018

Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is early-onset microsatellite and chromosomally stable colorectal cancer a hallmark of a genetic susceptibility syndrome?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p16 expression in colorectal adenocarcinoma: marker of aggressiveness and morphological types

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant expression of pRb and p16(INK4), alone or in combination, indicates poor outcome after resection in patients with colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant p16((INK4a)) methylation is a frequent event in colorectal cancers: prognostic value and relation to mRNA expression and immunoreactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component

1 reference

https://pubmed.ncbi.nlm.nih.gov/20473920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/IJC.25432

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20473920%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20473920%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20473920%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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